Clinical trials based on mesenchymal stromal cells are exponentially increasing: where are we in recent years?
U Galderisi, G Peluso, G Di Bernardo - Stem cell reviews and reports, 2022 - Springer
Mesenchymal stromal cells (MSCs), present in the stromal component of several tissues,
include multipotent stem cells, progenitors, and differentiated cells. MSCs have quickly …
include multipotent stem cells, progenitors, and differentiated cells. MSCs have quickly …
Immunomodulatory mechanisms of mesenchymal stem cells and their potential clinical applications
Y Huang, Q Wu, PKH Tam - International Journal of Molecular Sciences, 2022 - mdpi.com
Mesenchymal stem cells (MSCs) are multipotent stem cells with the capacity of self-renewal,
homing, and low immunogenicity. These distinct biological characteristics have already …
homing, and low immunogenicity. These distinct biological characteristics have already …
Review of the current trends in clinical trials involving induced pluripotent stem cells
JY Kim, Y Nam, YA Rim, JH Ju - Stem cell reviews and reports, 2022 - Springer
In 2006, the induced pluripotent stem cell (iPSC) was presented to the world, paving the way
for the development of a magnitude of novel therapeutic alternatives, addressing a diverse …
for the development of a magnitude of novel therapeutic alternatives, addressing a diverse …
The current status of mesenchymal stromal cells: controversies, unresolved issues and some promising solutions to improve their therapeutic efficacy
Mesenchymal stromal cells (MSCs) currently constitute the most frequently used cell type in
advanced therapies with different purposes, most of which are related with inflammatory …
advanced therapies with different purposes, most of which are related with inflammatory …
Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy
M Chehelgerdi, F Behdarvand Dehkordi… - Molecular Cancer, 2023 - Springer
The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …
Advances in mesenchymal stem cell therapy for immune and inflammatory diseases: Use of cell-free products and human pluripotent stem cell-derived mesenchymal …
LT Wang, KJ Liu, HK Sytwu, ML Yen… - Stem cells translational …, 2021 - academic.oup.com
Mesenchymal stem cell therapy (MSCT) for immune and inflammatory diseases continues to
be popular based on progressive accumulation of preclinical mechanistic evidence. This …
be popular based on progressive accumulation of preclinical mechanistic evidence. This …
Mesenchymal stromal cells for the treatment of graft versus host disease
K Kelly, JEJ Rasko - Frontiers in immunology, 2021 - frontiersin.org
Graft versus host disease (GvHD) is a life-threating complication of allogeneic hematopoietic
stem cell transplantation, which is initially treated with high dose corticosteroids …
stem cell transplantation, which is initially treated with high dose corticosteroids …
Current status of clinical trials assessing mesenchymal stem cell therapy for graft versus host disease: a systematic review
Y Li, J Hao, Z Hu, YG Yang, Q Zhou, L Sun… - Stem Cell Research & …, 2022 - Springer
Background Graft-versus-host disease (GVHD) is a common fatal complication of
hematopoietic stem cell transplantation (HSCT), where steroids are used as a treatment …
hematopoietic stem cell transplantation (HSCT), where steroids are used as a treatment …
Culture-expanded mesenchymal stromal cell therapy: does it work in knee osteoarthritis? A pathway to clinical success
Osteoarthritis (OA) is a degenerative multifactorial disease with concomitant structural,
inflammatory, and metabolic changes that fluctuate in a temporal and patient-specific …
inflammatory, and metabolic changes that fluctuate in a temporal and patient-specific …
Mesenchymal stem cells as a bio organ for treatment of female infertility
Female infertility is a global medical condition that can be caused by various disorders of the
reproductive system, including premature ovarian failure (POF), polycystic ovary syndrome …
reproductive system, including premature ovarian failure (POF), polycystic ovary syndrome …