International consensus statement on allergy and rhinology: Allergic rhinitis–2023

SK Wise, C Damask, LT Roland, C Ebert… - International forum of …, 2023 - Wiley Online Library
Background In the 5 years that have passed since the publication of the 2018 International
Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis …

T helper (Th) cell profiles in pregnancy and recurrent pregnancy losses: Th1/Th2/Th9/Th17/Th22/Tfh cells

W Wang, N Sung, A Gilman-Sachs… - Frontiers in …, 2020 - frontiersin.org
During pregnancy, various immune effectors and molecules participating in the immune-
microenvironment establish specific maternal tolerance toward the semi-allogeneic fetus …

Mucins in intestinal mucosal defense and inflammation: learning from clinical and experimental studies

JA Grondin, YH Kwon, PM Far, S Haq… - Frontiers in …, 2020 - frontiersin.org
Throughout the gastrointestinal (GI) tract, a distinct mucus layer composed of highly
glycosylated proteins called mucins plays an essential role in providing lubrication for the …

IL-2 regulates tumor-reactive CD8+ T cell exhaustion by activating the aryl hydrocarbon receptor

Y Liu, N Zhou, LI Zhou, J Wang, Y Zhou, T Zhang… - Nature …, 2021 - nature.com
CD8+ T cell exhaustion dampens antitumor immunity. Although several transcription factors
have been identified that regulate T cell exhaustion, the molecular mechanisms by which …

Helper T cell differentiation

J Saravia, NM Chapman, H Chi - Cellular & molecular immunology, 2019 - nature.com
CD4+ T helper cells are key regulators of host health and disease. In the original model,
specialized subsets of T helper cells are generated following activation through lineage …

Interleukin-33 in health and disease

FY Liew, JP Girard, HR Turnquist - Nature Reviews Immunology, 2016 - nature.com
Abstract Interleukin-33 (IL-33)—a member of the IL-1 family—was originally described as an
inducer of type 2 immune responses, activating T helper 2 (TH2) cells and mast cells. Now …

Innate lymphoid cells as regulators of immunity, inflammation and tissue homeostasis

CSN Klose, D Artis - Nature immunology, 2016 - nature.com
Research over the last 7 years has led to the formal identification of innate lymphoid cells
(ILCs), increased the understanding of their tissue distribution and has established essential …

The ST2/IL-33 axis in immune cells during inflammatory diseases

B Griesenauer, S Paczesny - Frontiers in immunology, 2017 - frontiersin.org
Il1rl1 (also known as ST2) is a member of the IL-1 superfamily, and its only known ligand is
IL-33. ST2 exists in two forms as splice variants: a soluble form (sST2), which acts as a …

The biology of innate lymphoid cells

D Artis, H Spits - Nature, 2015 - nature.com
The innate immune system is composed of a diverse array of evolutionarily ancient
haematopoietic cell types, including dendritic cells, monocytes, macrophages and …

IL-9 aggravates SARS-CoV-2 infection and exacerbates associated airway inflammation

S Sadhu, R Dalal, J Dandotiya, A Binayke… - Nature …, 2023 - nature.com
SARS-CoV-2 infection is known for causing broncho-alveolar inflammation. Interleukin 9 (IL-
9) induces airway inflammation and bronchial hyper responsiveness in respiratory viral …