Parkinson's disease and microRNAs: A duel between inhibition and stimulation of apoptosis in neuronal cells

MJ Saadh, A Faisal, M Adil, RS Zabibah… - Molecular …, 2024 - Springer
Parkinson's disease (PD) is one of the most prevalent diseases of central nervous system
that is caused by degeneration of the substantia nigra's dopamine-producing neurons …

[HTML][HTML] Developmental origins of Parkinson disease: Improving the rodent models

I Jiménez-Salvador, P Meade, E Iglesias… - Ageing Research …, 2023 - Elsevier
Numerous pesticides are inhibitors of the oxidative phosphorylation system. Oxidative
phosphorylation dysfunction adversely affects neurogenesis and often accompanies …

Fibrinogen and Complement Factor H Are Promising CSF Protein Biomarkers for Parkinson's Disease with Cognitive Impairment─ A Proteomics–ELISA-Based Study

A Naskar, A Stezin, A Dharmappa… - ACS chemical …, 2022 - ACS Publications
Parkinson's disease (PD) with cognitive impairment (PDCI) is essentially diagnosed through
clinical and neuropsychological examinations. There is a need to identify biomarkers to …

Apoptotic factors and mitochondrial complexes assist determination of strain-specific susceptibility of mice to Parkinsonian neurotoxin MPTP

H Yarreiphang, DJ Vidyadhara, AK Nambisan… - Molecular …, 2023 - Springer
Identification of genetic mutations in Parkinson's disease (PD) promulgates the genetic
nature of disease susceptibility. Resilience-associated genes being unknown till date, the …

Fibrinogen and complement factor H: The two crucial markers of Parkinson's disease with cognitive impairment

A Naskar, M Sachin, S Sengupta, P Bhadrachalam… - bioRxiv, 2023 - biorxiv.org
Animal model-assisted validation is vital for biomarker studies. It provides better means for
understanding disease pathogenesis and opens avenues for addressing therapeutics. Our …

Age-associated myelin decompaction and CNPase expression differ in magnitude in the substantia nigra of MPTP-sensitive C57BL/6J mice and MPTP-resistant CD-1 …

PL Abhilash, U Bharti, L Anand, BKC Sagar, PA Alladi - 2023 - researchsquare.com
Opposing phenomena of both oligodendrogliosis and oligodendroglial degeneration is
reported in the striatum of MPTP-injected mice model of Parkinson's disease (PD); reducing …