The single chirality of biological molecules in terrestrial biology raises more questions than
certitudes about its origin. The emergence of biological homochirality (BH) and its …

Spontaneous deracemizations is a challenging, multidisciplinary subject in current chirality
research. In the absence of any chiral inductors, an achiral substance or a racemic …

Autocatalytic models for the emergence of homochirality have been of interest for more than
half a century. The sole experimental example of such an amplifying autocatalytic reaction is …

There is a need for the preparation of enantiomerically pure compounds for various
applications. An efficient approach to achieve this goal is asymmetric catalysis. The chiral …

The overwhelmingly homochiral nature of life has left a puzzle as to whether mirror-image
biological systems based on a chirally inverted version of molecular machinery could also …

" How did life originate and why were left-handed molecules selected for its architecture?"
This question of high public and interdisciplinary scientific interest is the central theme of this …

Conspectus Amplification of enantiomeric excess (ee) is a key feature for the chemical
evolution of biological homochirality from the origin of chirality. We describe the amplification …

The Soai reaction has profoundly impacted chemists' perspective of autocatalysis, chiral
symmetry breaking, absolute asymmetric synthesis and its role in the origin of biological …

Since the model proposed by Frank (Frank FC, Biochem Biophys Acta 1953; 11: 459–463),
several alternative models have been developed to explain how an asymmetric non …

We found that chiral 5-pyrimidyl alkanols are highly enantioselective asymmetric
autocatalysts forthe addition of i-Pr 2 Zn to the corresponding aldehyde. Asymmetric …