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Estrogen receptor function: impact on the human endometrium
The physiological role of estrogen in the female endometrium is well established. On the
basis of responses to steroid hormones (progesterone, androgen, and estrogen), the …
basis of responses to steroid hormones (progesterone, androgen, and estrogen), the …
Estrogen receptor signaling in the immune system
The immune system functions in a sexually dimorphic manner, with females exhibiting more
robust immune responses than males. However, how female sex hormones affect immune …
robust immune responses than males. However, how female sex hormones affect immune …
The Concise Guide to PHARMACOLOGY 2013/14: G protein‐coupled receptors
Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …
Twenty years of the G protein-coupled estrogen receptor GPER: Historical and personal perspectives
Estrogens play a critical role in many aspects of physiology, particularly female reproductive
function, but also in pathophysiology, and are associated with protection from numerous …
function, but also in pathophysiology, and are associated with protection from numerous …
Does GPER Really Function as a G Protein-Coupled Estrogen Receptor in vivo?
Estrogen can elicit pleiotropic cellular responses via a diversity of estrogen receptors (ERs)—
mediated genomic and rapid non-genomic mechanisms. Unlike the genomic responses …
mediated genomic and rapid non-genomic mechanisms. Unlike the genomic responses …
Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis
The adult skeleton regenerates by temporary cellular structures that comprise teams of
juxtaposed osteoclasts and osteoblasts and replace periodically old bone with new. A …
juxtaposed osteoclasts and osteoblasts and replace periodically old bone with new. A …
Estrogen carcinogenesis in breast cancer
Estrogen Carcinogenesis in Breast Cancer | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …
content The New England Journal of Medicine homepage Advanced Search SEARCH …
Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes
L Björnström, M Sjöberg - Molecular endocrinology, 2005 - academic.oup.com
Estrogen receptors (ERs) act by regulating transcriptional processes. The classical
mechanism of ER action involves estrogen binding to receptors in the nucleus, after which …
mechanism of ER action involves estrogen binding to receptors in the nucleus, after which …
Estrogen-Induced Activation of Erk-1 and Erk-2 Requires the G Protein-Coupled Receptor Homolog, GPR30, and Occurs via Trans-Activation of the Epidermal Growth …
Estrogen rapidly activates the mitogen-activated protein kinases, Erk-1 and Erk-2, via an as
yet unknown mechanism. Here, evidence is provided that estrogen-induced Erk-1/-2 …
yet unknown mechanism. Here, evidence is provided that estrogen-induced Erk-1/-2 …
Estrogen receptor null mice: what have we learned and where will they lead us?
JF Couse, KS Korach - Endocrine reviews, 1999 - academic.oup.com
Elwood Jensen and Jack Gorski had spent 10 yr providing experimental evidence to support
the concept of an intracellular “receptor” protein for steroid hormones. Their combined work …
the concept of an intracellular “receptor” protein for steroid hormones. Their combined work …