Herpes Simplex virus, human papillomavirus, and cervical cancer: overview, relationship, and treatment implications

DG Sausen, O Shechter, ES Gallo, H Dahari… - Cancers, 2023 - mdpi.com
Simple Summary Many different viruses are known to cause cancer. It is well known that
human papillomavirus is a causative agent of cervical carcinoma. What is more controversial …

The 2023 report on the proteome from the HUPO human proteome project

GS Omenn, L Lane, CM Overall… - Journal of proteome …, 2024 - ACS Publications
Since 2010, the Human Proteome Project (HPP), the flagship initiative of the Human
Proteome Organization (HUPO), has pursued two goals:(1) to credibly identify the protein …

Human cytomegalovirus UL138 interaction with USP1 activates STAT1 in infection

K Zarrella, P Longmire, S Zeltzer… - PLoS …, 2023 - journals.plos.org
Innate immune responses are crucial for limiting virus infection. However, viruses often
hijack our best defenses for viral objectives. Human Cytomegalovirus (HCMV) is a beta …

Story of an infection: Viral dynamics and host responses in the Caenorhabditis elegans–Orsay virus pathosystem

VG Castiglioni, MJ Olmo-Uceda, A Villena-Giménez… - Science …, 2024 - science.org
Orsay virus (OrV) is the only known natural virus affecting Caenorhabditis elegans, with
minimal impact on the animal's fitness due to its robust innate immune response. This study …

Infection-induced lysine lactylation enables herpesvirus immune evasion

MD Tyl, VU Merengwa, IM Cristea - Science Advances, 2025 - science.org
Aerobic glycolysis is a hallmark of many viral infections, leading to substantial accumulation
of lactate. However, the regulatory roles of lactate during viral infections remain poorly …

[HTML][HTML] Endogenous metabolite N-chlorotaurine attenuates antiviral responses by facilitating IRF3 oxidation

Y Yang, C Wang, W Sun, Y Fu, X Wu, C Zhao, H Song… - Redox Biology, 2025 - Elsevier
Cellular microenvironments critically control the activation of innate immune responses. N-
chlorotaurine (Tau-Cl) is an endogenous metabolite that is markedly produced and secreted …

A Direct Approach for Living Biomembrane Printing on a Nanoparticle

R Mizuta, E Kanao, K Ukyo, S Kuwada, S Sawada… - Nano Letters, 2024 - ACS Publications
Biomembrane coating technologies have been developed to equip synthetic nanomaterials
with natural biointerfaces. We report a one-step method for nondestructively coating the …

Transmission of unfolded protein response—a regulator of disease progression, severity, and spread in virus infections

V Prasad - mBio, 2025 - journals.asm.org
The unfolded protein response (UPR) is a cell-autonomous stress response aimed at
restoring homeostasis due to the accumulation of misfolded proteins in the endoplasmic …

Peculiar transcriptional reprogramming with functional impairment of dendritic cells upon exposure to transformed HTLV-1-infected cells

A Carcone, F Mortreux, S Alais, C Mathieu… - PLoS …, 2024 - journals.plos.org
Manipulation of immune cell functions, independently of direct infection of these cells,
emerges as a key process in viral pathophysiology. Chronic infection by Human T-cell …

Neuron-associated retroelement-derived protein Arc/Arg3. 1 assists in the early stages of alphaherpesvirus infection in human neuronal cells

H Kobayashi, M Yasukochi, M Horie, Y Orba, H Sawa… - PloS one, 2024 - journals.plos.org
Alphaherpesviruses, including herpes simplex virus type 1 (HSV-1) and pseudorabies virus
(PRV), are neurotropic double-stranded DNA viruses. Alphaherpesviruses control the …