SUMMARY and the genetics of these coronaviruses. Studies reveal that SARS-CoV-2 is
very similar in structure and pathogenicity with SARS-CoV, but the most important structural …

Abstract Coronaviruses (CoVs), enveloped positive-sense RNA viruses, are characterized
by club-like spikes that project from their surface, an unusually large RNA genome, and a …

The RNA-guided endonuclease Cas9 is a versatile genome-editing tool with a broad range
of applications from therapeutics to functional annotation of genes. Cas9 creates double …

Middle East respiratory syndrome (MERS) is a highly lethal respiratory disease caused by a
novel single-stranded, positive-sense RNA betacoronavirus (MERS-CoV). Dromedary …

The source of the severe acute respiratory syndrome (SARS) epidemic was traced to wildlife
market civets and ultimately to bats. Subsequent hunting for novel coronaviruses (CoVs) led …

Outbreaks of emerging infections present health professionals with the unique challenge of
trying to select appropriate pharmacologic treatments in the clinic with little time available for …

Bats have been recognized as the natural reservoirs of a large variety of viruses. Special
attention has been paid to bat coronaviruses as the two emerging coronaviruses which have …

The first known cases of Middle East respiratory syndrome (MERS), associated with infection
by a novel coronavirus (CoV), occurred in 2012 in Jordan but were reported retrospectively …

Outbreaks of Middle East respiratory syndrome (MERS) raise questions about the
prevalence and evolution of the MERS coronavirus (CoV) in its animal reservoir. Our …

Abstract Background. The Middle East respiratory syndrome (MERS) coronavirus causes
isolated cases and outbreaks of severe respiratory disease. Essential features of the natural …