Adipogenesis: a complex interplay of multiple molecular determinants and pathways
The formation of adipocytes during embryogenesis has been largely understudied.
However, preadipocytes appear to originate from multipotent mesenchymal stromal/stem …
However, preadipocytes appear to originate from multipotent mesenchymal stromal/stem …
Mammalian Krüppel-like factors in health and diseases
The Krüppel-like factor (KLF) family of transcription factors regulates diverse biological
processes that include proliferation, differentiation, growth, development, survival, and …
processes that include proliferation, differentiation, growth, development, survival, and …
Single-cell dissection of the obesity-exercise axis in adipose-muscle tissues implies a critical role for mesenchymal stem cells
Exercise training is critical for the prevention and treatment of obesity, but its underlying
mechanisms remain incompletely understood given the challenge of profiling …
mechanisms remain incompletely understood given the challenge of profiling …
Molecular mechanisms of adipogenesis: the anti-adipogenic role of AMP-activated protein kinase
Obesity is now a widespread disorder, and its prevalence has become a critical concern
worldwide, due to its association with common co-morbidities like cancer, cardiovascular …
worldwide, due to its association with common co-morbidities like cancer, cardiovascular …
New developments in adipogenesis
The obesity epidemic has focused attention on adipose tissue and the development of fat
cells (ie adipocytes), which is known as adipogenesis. Peroxisome proliferator-activated …
cells (ie adipocytes), which is known as adipogenesis. Peroxisome proliferator-activated …
Adipogenesis at a glance
The formation of adipocytes from precursor stem cells involves a complex and highly
orchestrated programme of gene expression. Our understanding of the basic network of …
orchestrated programme of gene expression. Our understanding of the basic network of …
Transcriptional regulation of adipogenesis
PM de Sá, AJ Richard, H Hang… - Comprehensive …, 2011 - Wiley Online Library
Adipocytes are the defining cell type of adipose tissue. Once considered a passive
participant in energy storage, adipose tissue is now recognized as a dynamic organ that …
participant in energy storage, adipose tissue is now recognized as a dynamic organ that …
Transcriptional networks and chromatin remodeling controlling adipogenesis
Adipocyte differentiation is tightly controlled by a transcriptional cascade, which directs the
extensive reprogramming of gene expression required to convert fibroblast-like precursor …
extensive reprogramming of gene expression required to convert fibroblast-like precursor …
Targeted deletion of autophagy-related 5 (atg5) impairs adipogenesis in a cellular model and in mice
R Baerga, Y Zhang, PH Chen, S Goldman, SV ** - Autophagy, 2009 - Taylor & Francis
Mammalian white adipocytes have a unique structure in which nearly the entire cell volume
is occupied by a single large lipid droplet, while the surrounding cytoplasm occupies …
is occupied by a single large lipid droplet, while the surrounding cytoplasm occupies …
Krüppel-like factors: crippling and uncrippling metabolic pathways
Krüppel-like factors (KLFs) are deoxyribonucleic acid–binding transcriptional factors that
regulate various pathways that control metabolism and other cellular mechanisms. Various …
regulate various pathways that control metabolism and other cellular mechanisms. Various …