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[HTML][HTML] Folate and carcinogenesis: an integrated scheme
Collectively, the evidence from epidemiologic, animal and human studies strongly suggests
that folate status modulates the risk of develo** cancers in selected tissues, the most …
that folate status modulates the risk of develo** cancers in selected tissues, the most …
Folate and carcinogenesis: evidence, mechanisms, and implications
YI Kim - The Journal of nutritional biochemistry, 1999 - Elsevier
Folate, a water-soluble B vitamin, has recently garnered much attention because of its
purported role in the pathogenesis of cardiovascular disease, 1–4 neural tube defects, 5–7 …
purported role in the pathogenesis of cardiovascular disease, 1–4 neural tube defects, 5–7 …
[HTML][HTML] Knowledge gaps in understanding the metabolic and clinical effects of excess folates/folic acid: a summary, and perspectives, from an NIH workshop
Folate, an essential nutrient found naturally in foods in a reduced form, is present in dietary
supplements and fortified foods in an oxidized synthetic form (folic acid). There is …
supplements and fortified foods in an oxidized synthetic form (folic acid). There is …
Folic acid for the prevention of colorectal adenomas: a randomized clinical trial
ContextLaboratory and epidemiological data suggest that folic acid may have an
antineoplastic effect in the large intestine. ObjectiveTo assess the safety and efficacy of folic …
antineoplastic effect in the large intestine. ObjectiveTo assess the safety and efficacy of folic …
[HTML][HTML] Unmetabolized folic acid in plasma is associated with reduced natural killer cell cytotoxicity among postmenopausal women
Folic acid (FA) supplements and food fortification are used to prevent neural tube defects
and to lower plasma homocysteine. Through exposure to food fortification and vitamin …
and to lower plasma homocysteine. Through exposure to food fortification and vitamin …
Free radical scavenging behavior of folic acid: evidence for possible antioxidant activity
The free radical scavenging properties and possible antioxidant activity of folic acid are
reported. Pulse radiolysis technique is employed to study the one-electron oxidation of folic …
reported. Pulse radiolysis technique is employed to study the one-electron oxidation of folic …
DNA methylation, cancer susceptibility, and nutrient interactions
CD Davis, EO Uthus - Experimental biology and medicine, 2004 - journals.sagepub.com
DNA methylation is an important epigenetic mechanism of transcriptional control. DNA
methylation plays an essential role in maintaining cellular function, and changes in …
methylation plays an essential role in maintaining cellular function, and changes in …
Folate and colorectal cancer: An evidence‐based critical review
YI Kim - Molecular nutrition & food research, 2007 - Wiley Online Library
Currently available evidence from epidemiologic, animal, and intervention studies does not
unequivocally support the role of folate, a water‐soluble B vitamin and important cofactor in …
unequivocally support the role of folate, a water‐soluble B vitamin and important cofactor in …
[HTML][HTML] Role of folate in colon cancer development and progression
YI Kim - The Journal of nutrition, 2003 - Elsevier
Folate, a water-soluble B vitamin and important cofactor in 1-carbon transfer, is an important
nutritional factor that may modulate the development of colorectal cancer. Epidemiologic …
nutritional factor that may modulate the development of colorectal cancer. Epidemiologic …
Folate and cancer: how DNA damage, repair and methylation impact on colon carcinogenesis
SJ Duthie - Journal of inherited metabolic disease, 2011 - Springer
Inappropriate diet may contribute to one third of cancer deaths. Folates, a group of water-
soluble B vitamins present in high concentrations in green, leafy vegetables, maintain DNA …
soluble B vitamins present in high concentrations in green, leafy vegetables, maintain DNA …