Brain metastases affect a significant percentage of patients with advanced extracranial
malignancies. Yet, the incidence of brain metastases remains poorly described, largely due …

Brain metastases occur commonly in patients with advanced solid malignancies. Yet, less is
known about brain metastases than cancer-related entities of similar incidence. Advances in …

Purpose This guideline provides updated evidence-based recommendations addressing
recent developments in the management of patients with brain metastases, including …

Leptomeningeal metastasis (LM), or spread of cancer to the cerebrospinal fluid (CSF)–filled
space surrounding the central nervous system, is a fatal complication of cancer. Entry into …

Purpose The purpose of this critical review is to summarize the literature specific to single-
fraction stereotactic radiosurgery (SRS) and multiple-fraction stereotactic radiation therapy …

Purpose Breast cancer brain metastases (BCBM) are becoming an increasingly common
diagnosis due to improved systemic control and more routine surveillance imaging …

Introduction Various treatment options exist to salvage stereotactic radiosurgery (SRS)
failures for brain metastases, including repeat SRS and hypofractionated SRS (HSRS). Our …

The incidence of brain metastasis is increasing as improvements in systemic therapy lead to
increased survival. This provides new and challenging clinical decisions for patients who …

Leptomeningeal disease (LMD) is a devastating complication of cancer with a particularly
poor prognosis. Among solid tumours, malignant melanoma (MM) has one of the highest …

Abstract In February 2018, the Melanoma Research Foundation and the Moffitt Cancer
Center hosted the Second Summit on Melanoma Central Nervous System Metastases in …