The human body is full of an extensive number of commensal microbes, consisting of
bacteria, viruses, and fungi, collectively termed the human microbiome. The initial …

Besides damaging the brain, stroke causes systemic changes, including to the
gastrointestinal system. A growing body of evidence supports the role of the gut and its …

Microglial function declines during aging. The interaction of microglia with the gut microbiota
has been well characterized during development and adulthood but not in aging. Here, we …

Rationale: The elderly experience profound systemic responses after stroke, which
contribute to higher mortality and more severe long-term disability. Recent studies have …

Background: Several studies suggested an important role of the gut microbiota in the
pathophysiology of neurological disorders, implying that alteration of the gut microbiota …

Hematopoietic stem cell (HSC) aging is accompanied by hematopoietic reconstitution
dysfunction, including loss of regenerative and engraftment ability, myeloid differentiation …

Recent research on the gut microbiome has revealed the influence of gut microbiota (GM)
on ischemic stroke pathogenesis and treatment outcomes. Alterations in the diversity …

Ischaemic stroke is a leading cause of disability and death for which no acute treatments
exist beyond recanalization. The development of novel therapies has been repeatedly …

The human microbiota comprises trillions of symbiotic microorganisms and is involved in
regulating gastrointestinal (GI), immune, nervous system and metabolic homeostasis …

The microbiota-gut-brain-axis (MGBA) is a bidirectional communication network between gut
microbes and their host. Many environmental and host-related factors affect the gut …