Frontotemporal dementia (FTD), the second most common type of presenile dementia, is a
heterogeneous neurodegenerative disease characterized by progressive behavioural …

Progressive and relatively circumscribed loss of semantic knowledge, referred to as
semantic dementia (SD) which falls under the broader umbrella of frontotemporal dementia …

Rapid and efficient protocols to generate oligodendrocytes (OL) from human induced
pluripotent stem cells (iPSC) are currently lacking, but may be a key technology to …

The typical presentation of semantic dementia is associated with marked, left predominant
anterior temporal lobe atrophy and with changes in language. About 30% of individuals …

The consensus criteria for the diagnosis and classification of primary progressive aphasia
(PPA) have served as an important tool in studying this group of disorders. However, a large …

Develo** and validating sensitive biomarkers for the presymptomatic stage of familial
frontotemporal dementia is an important step in early diagnosis and for the design of future …

Frontotemporal dementia refers to a group of progressive neurodegenerative syndromes
usually caused by the accumulation of pathological tau or TDP-43 proteins. The effects of …

Much of human behaviour is motivated by the drive to experience pleasure. The capacity to
envisage pleasurable outcomes and to engage in goal-directed behaviour to secure these …

Autobiographical memory represents a defining feature of human cognition, enabling us to
vividly re‐experience salient events from the personal past. By mentally traversing different …

Frontotemporal dementia (FTD) is a clinically and neuroanatomically heterogeneous
neurodegenerative disorder with multiple underlying genetic and pathological causes …