Onchocerciasis-associated epilepsy: an update and future perspectives

A Hadermann, LJ Amaral, G Van Cutsem… - Trends in …, 2023‏ - cell.com
Onchocerciasis-associated epilepsy (OAE) is an important neglected public health problem
in areas with high ongoing onchocerciasis transmission. The risk that children in such areas …

Onchocerca volvulus and epilepsy: A comprehensive review using the Bradford Hill criteria for causation

R Colebunders, AK Njamnshi, S Menon… - PLoS neglected …, 2021‏ - journals.plos.org
Background The possibility that onchocerciasis may cause epilepsy has been suggested for
a long time, but thus far, an etiological link has not been universally accepted. The objective …

Onchocerciasis (river blindness)–more than a century of research and control

NW Brattig, RA Cheke, R Garms - Acta Tropica, 2021‏ - Elsevier
This review summarises more than a century of research on onchocerciasis, also known as
river blindness, and its control. River blindness is an infection caused by the tissue filaria …

[HTML][HTML] Case definitions for onchocerciasis-associated epilepsy and nodding syndrome: A focused review

G Van Cutsem, JNS Fodjo, MCJ Dekker… - … : European Journal of …, 2023‏ - Elsevier
Onchocerciasis-associated epilepsy (OAE) is an important but neglected public health
problem in onchocerciasis-endemic areas with insufficient or inadequate onchocerciasis …

The role of the Maridi Dam in causing an onchocerciasis-associated epilepsy epidemic in Maridi, South Sudan: an epidemiological, sociological, and entomological …

TL Lakwo, S Raimon, M Tionga, JN Siewe Fodjo… - Pathogens, 2020‏ - mdpi.com
Background: An epilepsy prevalence of 4.4% was documented in onchocerciasis-endemic
villages close to the Maridi River in South Sudan. We investigated the role of the Maridi dam …

Prevalence and incidence of nodding syndrome and other forms of epilepsy in onchocerciasis-endemic areas in northern Uganda after the implementation of …

N Gumisiriza, F Mubiru, JN Siewe Fodjo… - Infectious Diseases of …, 2020‏ - Springer
Background Around 2007, a nodding syndrome (NS) epidemic appeared in onchocerciasis-
endemic districts of northern Uganda, where ivermectin mass distribution had never been …

Epidemiology of onchocerciasis-associated epilepsy in the Mbam and Sanaga river valleys of Cameroon: impact of more than 13 years of ivermectin

JN Siewe Fodjo, G Tatah, EN Tabah, L Ngarka… - Infectious Diseases of …, 2018‏ - Springer
Background A high epilepsy prevalence has been reported in several onchocerciasis-
endemic villages along the Mbam and Sanaga river valleys in Cameroon, including Bilomo …

From river blindness to river epilepsy: Implications for onchocerciasis elimination programmes

R Colebunders, JN Siewe Fodjo… - PLoS neglected …, 2019‏ - journals.plos.org
Current onchocerciasis elimination programmes do not include identification and
management of onchocerciasis-associated epilepsy (OAE) in their strategies. Creating …

[HTML][HTML] High prevalence of onchocerciasis-associated epilepsy in villages in Maridi County, Republic of South Sudan: A community-based survey

R Colebunders, JY Carter, PC Olore, K Puok… - Seizure, 2018‏ - Elsevier
Purpose To determine the prevalence and incidence of epilepsy in an onchocerciasis
endemic region of South Sudan. Methods In May 2018, a door-to-door household survey …

Neuroinflammation and not tauopathy is a predominant pathological signature of nodding syndrome

A Hotterbeekx, M Lammens, R Idro… - … of Neuropathology & …, 2019‏ - academic.oup.com
Nodding syndrome (NS) is an epileptic disorder occurring in children in African
onchocerciasis endemic regions. Here, we describe the pathological changes in 9 …