Semantic similarity and machine learning with ontologies

M Kulmanov, FZ Smaili, X Gao… - Briefings in …, 2021 - academic.oup.com
Ontologies have long been employed in the life sciences to formally represent and reason
over domain knowledge and they are employed in almost every major biological database …

nhKcr: a new bioinformatics tool for predicting crotonylation sites on human nonhistone proteins based on deep learning

YZ Chen, ZZ Wang, Y Wang, G Ying… - Briefings in …, 2021 - academic.oup.com
Lysine crotonylation (Kcr) is a newly discovered type of protein post-translational
modification and has been reported to be involved in various pathophysiological processes …

Owl2vec*: Embedding of owl ontologies

J Chen, P Hu, E Jimenez-Ruiz, OM Holter… - Machine Learning, 2021 - Springer
Semantic embedding of knowledge graphs has been widely studied and used for prediction
and statistical analysis tasks across various domains such as Natural Language Processing …

Ontoprotein: Protein pretraining with gene ontology embedding

N Zhang, Z Bi, X Liang, S Cheng, H Hong… - arxiv preprint arxiv …, 2022 - arxiv.org
Self-supervised protein language models have proved their effectiveness in learning the
proteins representations. With the increasing computational power, current protein language …

MARPPI: boosting prediction of protein–protein interactions with multi-scale architecture residual network

X Li, P Han, W Chen, C Gao, S Wang… - Briefings in …, 2023 - academic.oup.com
Protein–protein interactions (PPIs) are a major component of the cellular biochemical
reaction network. Rich sequence information and machine learning techniques reduce the …

Contextual semantic embeddings for ontology subsumption prediction

J Chen, Y He, Y Geng, E Jiménez-Ruiz, H Dong… - World Wide Web, 2023 - Springer
Automating ontology construction and curation is an important but challenging task in
knowledge engineering and artificial intelligence. Prediction by machine learning …

El embeddings: Geometric construction of models for the description logic el++

M Kulmanov, W Liu-Wei, Y Yan… - arxiv preprint arxiv …, 2019 - arxiv.org
An embedding is a function that maps entities from one algebraic structure into another
while preserving certain characteristics. Embeddings are being used successfully for …

TransformerGO: predicting protein–protein interactions by modelling the attention between sets of gene ontology terms

I Ieremie, RM Ewing, M Niranjan - Bioinformatics, 2022 - academic.oup.com
Abstract Motivation Protein–protein interactions (PPIs) play a key role in diverse biological
processes but only a small subset of the interactions has been experimentally identified …

Drug target prediction through deep learning functional representation of gene signatures

H Chen, FJ King, B Zhou, Y Wang, CJ Canedy… - Nature …, 2024 - nature.com
Many machine learning applications in bioinformatics currently rely on matching gene
identities when analyzing input gene signatures and fail to take advantage of preexisting …

An integration of deep learning with feature embedding for protein–protein interaction prediction

Y Yao, X Du, Y Diao, H Zhu - PeerJ, 2019 - peerj.com
Protein–protein interactions are closely relevant to protein function and drug discovery.
Hence, accurately identifying protein–protein interactions will help us to understand the …