In this article, we reviewed the association between alcohol drinking and head and neck
cancer (HNC) and its subsites, using the available literature. Alcohol drinking is an …

Asthma is a chronic inflammatory lung disease that results in airflow limitation,
hyperreactivity, and airway remodeling. There is strong evidence that an imbalance between …

An essential resource for all scientists researching cellular responses to DNA damage.•
Introduces important new material reflective of the major changes and developments that …

Background Many reported associations between common genetic polymorphisms and
complex diseases have not been confirmed in subsequent studies. An exception could be …

Drug lag, recently discussed extensively in Japan, can be divided into two phases: clinical
development time and application review time. The former factor is still an important problem …

Childhood cancer is rare everywhere in the world, with age-standardized annual incidence
usually between 70 and 160 per million at age 0–14 years. Greater variation is seen …

Cytogenetic biomarkers have long been applied in surveillance of human genotoxic
exposure and early effects of genotoxic carcinogens. Due to their wide use, it has been …

Glutathione S-transferase P is abundantly expressed in some mammalian tissues,
particularly those associated with malignancies. While the enzyme can catalyze thioether …

Although cytosolic glutathione S-transferase (GST) enzymes occupy a key position in
biological detoxification processes, two of the most relevant human isoenzymes, GSTT1-1 …

Importance of the field: The Glutathione S-transferases (GSTs) have advanced beyond the
classic view of their role in metabolism and are encouraging scientists to assess new …