In-depth gaze at the astonishing mechanical behavior of bone: A review for designing bio-inspired hierarchical metamaterials

I Giorgio, M Spagnuolo, U Andreaus… - … and Mechanics of …, 2021 - journals.sagepub.com
In this review paper, some relevant models, algorithms, and approaches conceived to
describe the bone tissue mechanics and the remodeling process are showcased …

Multiscale mechanical modeling of skeletal muscle: a systemic review of the literature

A Loumeaud, P Pouletaut, SF Bensamoun… - Journal of Medical and …, 2024 - Springer
Purpose From the myofibrils to the whole muscle scale, muscle micro-constituents exhibit
passive and active mechanical properties, potentially coupled to electrical, chemical, and …

A multiphysics stimulus for continuum mechanics bone remodeling

D George, R Allena, Y Remond - Mathematics and Mechanics of Complex …, 2018 - msp.org
Bone remodelling is a complex phenomenon during which old and damage bone is
removed and replaced with new one to ensure the physiological functions of the skeletal …

Out-of-plane deformation reduction via inelastic hinges in fibrous metamaterials and simplified damage approach

M Spagnuolo, ME Yildizdag, X Pinelli… - … and Mechanics of …, 2022 - journals.sagepub.com
The mechanical behavior of fibrous metamaterials is mainly determined by the interactions
between the fibers composing the architecture. These interactions are usually of two …

Integrating molecular and cellular kinetics into a coupled continuum mechanobiological stimulus for bone reconstruction

D George, R Allena, Y Remond - Continuum Mechanics and …, 2019 - Springer
The development of multiphysics numerical models to predict bone reconstruction is a very
challenging task as it is a complex phenomenon where many biological, chemical and …

A new comprehensive approach for bone remodeling under medium and high mechanical load based on cellular activity

D George, R Allena, C Bourzac, S Pallu… - … and Mechanics of …, 2020 - msp.org
Most of the last century, bone remodeling models have been proposed based on the
observation that bone density is dependent on the intensity of the applied mechanical loads …

A model for the bio-mechanical stimulus in bone remodelling as a diffusive signalling agent for bones reconstructed with bio-resorbable grafts

R Allena, D Scerrato, AM Bersani, I Giorgio - Mechanics Research …, 2023 - Elsevier
Bone remodelling is a self-adaptive process occurring in bone living tissue to optimize its
mechanical response to environmental demands. Some cells, namely osteocytes, monitor …

Advances toward multiscale computational models of cartilage mechanics and mechanobiology

X Wang, CP Neu, DM Pierce - Current Opinion in Biomedical Engineering, 2019 - Elsevier
Across spatial scales, biological systems exhibit exquisite hierarchy in architecture and
function, leading to complex, observable phenomena. In the articular cartilage of our joints …

Mechanobiological stimuli for bone remodeling: mechanical energy, cell nutriments and mobility

D George, R Allena, Y Remond - Computer methods in …, 2017 - Taylor & Francis
2. Method Bone remodeling being the result of numerous mechanobiological mechanisms,
we propose to describe its evolution through the use of a biomechanical stimulus ΔS …

Heat conduction in multi-component step-wise FGMs

O Szlachetka, I Giorgio - Continuum Mechanics and Thermodynamics, 2024 - Springer
This paper provides a thorough investigation of a heat conduction problem that pertains to
tolerance modelling in layered materials made up of multiple components. These media are …