Circuit investigations with open-source miniaturized microscopes: past, present and future

D Aharoni, TM Hoogland - Frontiers in cellular neuroscience, 2019 - frontiersin.org
The ability to simultaneously image the spatiotemporal activity signatures from many
neurons during unrestrained vertebrate behaviors has become possible through the …

Imaging and analysis of genetically encoded calcium indicators linking neural circuits and behaviors

J Oh, C Lee, BK Kaang - The Korean Journal of Physiology & …, 2019 - synapse.koreamed.org
Confirming the direct link between neural circuit activity and animal behavior has been a
principal aim of neuroscience. The genetically encoded calcium indicator (GECI), which …

ezTrack: An open-source video analysis pipeline for the investigation of animal behavior

ZT Pennington, Z Dong, Y Feng, LM Vetere… - Scientific reports, 2019 - nature.com
Tracking animal behavior by video is one of the most common tasks in the life sciences.
Although commercial software exists for executing this task, they often present enormous …

Open source silicon microprobes for high throughput neural recording

L Yang, K Lee, J Villagracia… - Journal of neural …, 2020 - iopscience.iop.org
Objective. Microfabricated multielectrode arrays are widely used for high throughput
recording of extracellular neural activity, which is transforming our understanding of brain …

Network dysfunction in comorbid psychiatric illnesses and epilepsy

PLW Colmers, J Maguire - Epilepsy Currents, 2020 - journals.sagepub.com
The episodic nature of both epilepsy and psychiatric illnesses suggests that the brain
switches between healthy and pathological states. The most obvious example of transitions …

Imaging spinal cord activity in behaving animals

NA Nelson, X Wang, D Cook, EM Carey… - Experimental …, 2019 - Elsevier
The spinal cord is the primary neurological link between the brain and peripheral organs.
How important it is in everyday life is apparent in patients with spinal cord injury or …

Design of a high-resolution light field miniscope for volumetric imaging in scattering tissue

Y Chen, BO **ong, Y Xue, X **, J Greene… - Biomedical Optics …, 2020 - opg.optica.org
Integrating light field microscopy techniques with existing miniscope architectures has
allowed for volumetric imaging of targeted brain regions in freely moving animals. However …

WONOEP appraisal: Network concept from an imaging perspective

RC Wykes, HM Khoo, L Caciagli, H Blumenfeld… - …, 2019 - Wiley Online Library
Neuroimaging techniques applied to a variety of organisms—from zebrafish, to rodents to
humans—can offer valuable insights into neuronal network properties and their dysfunction …

Integrating adult neurogenesis and human brain organoid models to advance epilepsy and associated behavioral research

A Adeyeye, S Mirsadeghi, M Gutierrez, J Hsieh - Epilepsy & Behavior, 2024 - Elsevier
Epilepsy is a chronic neurological disorder characterized by recurring, unprovoked seizures,
asymmetrical electroencephalogram patterns, and other pathological abnormalities. The …

Hippocampal Encoding of Space Induced by Novel Auditory VR System Using One-Photon Miniaturized Microscope

S Gao - 2020 - search.proquest.com
In virtual reality settings, spatial navigation in animal models has traditionally been studied
using primarily visual cues. However, auditory cues play an important role in navigation for …