Functional circuitry of the retina

JB Demb, JH Singer - Annual review of vision science, 2015 - annualreviews.org
The mammalian retina is an important model system for studying neural circuitry: Its role in
sensation is clear, its cell types are relatively well defined, and its responses to natural …

Parallel processing of rod and cone signals: retinal function and human perception

WN Grimes, A Songco-Aguas… - Annual review of vision …, 2018 - annualreviews.org
We know a good deal about the operation of the retina when either rod or cone
photoreceptors provide the dominant input (ie, under very dim or very bright conditions) …

Restoration of vision after de novo genesis of rod photoreceptors in mammalian retinas

K Yao, S Qiu, YV Wang, SJH Park, EJ Mohns, B Mehta… - Nature, 2018 - nature.com
In zebrafish, Müller glia (MG) are a source of retinal stem cells that can replenish damaged
retinal neurons and restore vision. In mammals, however, MG do not spontaneously re-enter …

A circuit for gradient climbing in C. elegans chemotaxis

J Larsch, SW Flavell, Q Liu, A Gordus, DR Albrecht… - Cell reports, 2015 - cell.com
Animals have a remarkable ability to track dynamic sensory information. For example, the
nematode Caenorhabditis elegans can locate a diacetyl odor source across a 100,000-fold …

Retinal output changes qualitatively with every change in ambient illuminance

A Tikidji-Hamburyan, K Reinhard, H Seitter… - Nature …, 2015 - nature.com
The collective activity pattern of retinal ganglion cells, the retinal code, underlies higher
visual processing. How does the ambient illuminance of the visual scene influence this …

Rod and cone interactions in the retina

G Fain, AP Sampath - F1000Research, 2018 - pmc.ncbi.nlm.nih.gov
We have long known that rod and cone signals interact within the retina and can even
contribute to color vision, but the extent of these influences has remained unclear. New …

Homeostatic plasticity in the retina

MJ Fitzpatrick, D Kerschensteiner - Progress in Retinal and Eye Research, 2023 - Elsevier
Vision begins in the retina, whose intricate neural circuits extract salient features of the
environment from the light entering our eyes. Neurodegenerative diseases of the retina (eg …

Kainate receptors mediate signaling in both transient and sustained OFF bipolar cell pathways in mouse retina

BG Borghuis, LL Looger, S Tomita… - Journal of Neuroscience, 2014 - jneurosci.org
A fundamental question in sensory neuroscience is how parallel processing is implemented
at the level of molecular and circuit mechanisms. In the retina, it has been proposed that …

Divergent outer retinal circuits drive image and non-image visual behaviors

C Beier, U Bocchero, L Levy, Z Zhang, N **… - Cell reports, 2022 - cell.com
Image-and non-image-forming vision are essential for animal behavior. Here we use
genetically modified mouse lines to examine retinal circuits driving image-and non-image …

[HTML][HTML] Layers of inhibitory networks shape receptive field properties of AII amacrine cells

A Nath, WN Grimes, JS Diamond - Cell reports, 2023 - cell.com
In the retina, rod and cone pathways mediate visual signals over a billion-fold range in
luminance. AII (" A-two") amacrine cells (ACs) receive signals from both pathways via …