To date, interpretation of genomic information has focused on single variants conferring
disease risk, but most disorders of major public concern have a polygenic architecture …

In recent years, there have been prominent calls for a new social contract that accords a
more central role to citizens in health research. Typically, this has been understood as …

Direct-to-consumer (DTC) genetics services are increasingly popular, with tens of millions of
customers. Several DTC genealogy services allow users to upload genetic data to search for …

We explored the characteristics and motivations of people who, having obtained their
genetic or genomic data from Direct-To-Consumer genetic testing (DTC-GT) companies …

Motivation Genome-wide association studies (GWAS) present several computational and
statistical challenges for their data analysis, including knowledge discovery, interpretability …

Background Many aspects of our lives are now digitized and connected to the internet. As a
result, individuals are now creating and collecting more personal data than ever before. This …

Psychiatric treatment relies on a solid armamentarium of pharmacologic and
nonpharmacologic treatment modalities that perform reasonably well for many patients but …