The reactions of the tricarboxylic acid (TCA) cycle allow the controlled combustion of fat and
carbohydrate. In principle, TCA cycle intermediates are regenerated on every turn and can …

Cancer cells constantly face a fluctuating nutrient supply and interference with adaptive
responses might be an effective therapeutic approach. It has been discovered that in the …

Adiponectin is a secretory protein, primarily produced in adipocytes. However, low but
detectable expression of adiponectin can be observed in cell types beyond adipocytes …

Intestinal transport and sensing processes and their interconnection to metabolism are
relevant to pathologies such as malabsorption syndromes, inflammatory diseases, obesity …

Cancer cells undergo a metabolic rewiring in order to fulfill the energy and biomass
requirements. Cysteine is a pivotal organic compound that contributes for cancer metabolic …

Cancer cells frequently lack nutrients like glucose, due to insufficient vascular networks.
Mitochondrial phosphoenolpyruvate carboxykinase, PCK2, has recently been found to …

Abstract Background The Pacific oyster, Crassostrea gigas, is an economically important
shellfish around the world. Great efforts have been made to improve its growth rate through …

The liver is the major source of glucose production during fasting under normal
physiological conditions. However, the kidney may also contribute to maintaining glucose …

The intestinal epithelium critically contributes to oral bioavailability of drugs by constituting
an important site for drug absorption and metabolism. In particular, intestinal epithelial cells …

There is a growing body of evidence suggesting that the composition of intestinal flora plays
a significant role in regulating lipid metabolism. 2′, 3′, 5′-tri-O-acetyl-N6-(3 …