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Medicinal plants meet modern biodiversity science
Plants have been an essential source of human medicine for millennia. In this review, we
argue that a holistic, interdisciplinary approach to the study of medicinal plants that …
argue that a holistic, interdisciplinary approach to the study of medicinal plants that …
Cannabis sativa: origin and history, glandular trichome development, and cannabinoid biosynthesis
Z **e, Y Mi, L Kong, M Gao, S Chen… - Horticulture …, 2023 - academic.oup.com
Is Cannabis a boon or bane? Cannabis sativa has long been a versatile crop for fiber
extraction (industrial hemp), traditional Chinese medicine (hemp seeds), and recreational …
extraction (industrial hemp), traditional Chinese medicine (hemp seeds), and recreational …
[HTML][HTML] Engineering Nicotiana benthamiana as a platform for natural product biosynthesis
Nicotiana benthamiana is a model plant, widely used for research. The susceptibility of
young plants to Agrobacterium tumefaciens has been utilised for transient gene expression …
young plants to Agrobacterium tumefaciens has been utilised for transient gene expression …
Convergent evolution of berberine biosynthesis
Berberine is an effective antimicrobial and antidiabetic alkaloid, primarily extracted from
divergent botanical lineages, specifically Coptis (Ranunculales, early-diverging eudicot) and …
divergent botanical lineages, specifically Coptis (Ranunculales, early-diverging eudicot) and …
Haplotype-phased genome unveils the butylphthalide biosynthesis and homoploid hybrid origin of Ligusticum chuanxiong
Butylphthalide is one of the first-line drugs for ischemic stroke therapy, while no biosynthetic
enzyme for butylphthalide has been reported. Here, we present a haplotype-resolved …
enzyme for butylphthalide has been reported. Here, we present a haplotype-resolved …
Sesquiterpene lactones–insights into biosynthesis, regulation and signalling roles
Sesquiterpene lactones (STLs) are bitter tasting plant specialized metabolites derived from
farnesyl pyrophosphate (FPP) that contain a characteristic lactone ring. STLs can be found …
farnesyl pyrophosphate (FPP) that contain a characteristic lactone ring. STLs can be found …
Exploring the evolvability of plant specialized metabolism: uniqueness out of uniformity and uniqueness behind uniformity
E Ono, J Murata - Plant and Cell Physiology, 2023 - academic.oup.com
The huge structural diversity exhibited by plant specialized metabolites has primarily been
considered to result from the catalytic specificity of their biosynthetic enzymes. Accordingly …
considered to result from the catalytic specificity of their biosynthetic enzymes. Accordingly …
Engineering cannabinoid production in Saccharomyces cerevisiae
Phytocannabinoids are natural products with highly interesting pharmacological properties
mainly produced by plants. The production of cannabinoids in a heterologous host system …
mainly produced by plants. The production of cannabinoids in a heterologous host system …
[HTML][HTML] Plant synthetic biology for human health: advances in producing medicines in heterologous expression systems
Highlights•The “triple P” concept drives plant engineering for high-value natural
products.•Artificial organelles offer new opportunities to boost plant natural product …
products.•Artificial organelles offer new opportunities to boost plant natural product …
Cannabinoids function in defense against chewing herbivores in Cannabis sativa L.
In the decades since the first cannabinoids were identified by scientists, research has
focused almost exclusively on the function and capacity of cannabinoids as medicines and …
focused almost exclusively on the function and capacity of cannabinoids as medicines and …