Berberine, an isoquinoline alkaloid isolated from the Chinese herb Coptis chinensis and
other Berberis plants, has a wide range of pharmacological properties. Berberine can be …

Hyperlipidemia, defined as the presence of excess fat or lipids in the blood, has been
considered as a high-risk factor and key indicator of many metabolic diseases. The gut …

Cholesterol gallstone disease is a worldwide common disease. Cholesterol supersaturation
in gallbladder bile is the prerequisite for its pathogenesis, while the mechanism is not …

Human gut microbiome is a promising target for managing type 2 diabetes (T2D). Measures
altering gut microbiota like oral intake of probiotics or berberine (BBR), a bacteriostatic …

Cardiovascular and metabolic diseases (CVMD) are the leading causes of death worldwide,
underscoring the urgent necessity to develop new pharmacotherapies. Berberine (BBR) is …

Berberine is a natural pentacyclic isoquinoline alkaloid that has been isolated as the
principal component of many popular medicinal plants such as the genus Berberis, Coptis …

The increased incidence of metabolic diseases (eg, diabetes and obesity) has seriously
affected human health and life safety worldwide. It is of great significance to find effective …

Background Berberine (BBR), a natural compound extracted from Chinese herb, has been
shown to effectively attenuate nonalcoholic fatty liver disease (NAFLD) in clinic. However …

Berberine (BBR), an isoquinoline alkaloid, has been found in many plants, such as Coptis
chinensis Franch and Phellodendron chinense Schneid. Although BBR has a wide spectrum …

Few medications are available for meeting the increasing disease burden of nonalcoholic
fatty liver disease (NAFLD) and its progressive stage, nonalcoholic steatohepatitis (NASH) …