Stem cells are the future in tissue engineering and regeneration. In a co‐culture, stem cells
not only provide a target cell source with multipotent differentiation capacity, but can also act …

Silk is a remarkable biopolymer with a long history of medical use. Silk fabrications have a
robust track record for load-bearing applications, including surgical threads and meshes …

The interactions between corneal nerve, epithelium, and stroma are essential for
maintaining a healthy cornea. Thus, corneal tissue models that more fully mimic the …

Intervertebral disc degeneration might be amenable to stem cell therapy, but the required
cells are scarce. Here, we report the development of a protocol for directed in vitro …

Biologists increasingly use co-culture systems in which two or more cell types are grown in
cell culture together in order to better model cells' native microenvironments. Co-cultures are …

Limitations to the in vivo study of human nervous system development make it necessary to
design an in vitro model to evaluate the in vivo effects of surrounding tissues on …

Efficient derivation of neural cells from pluripotent stem cells remains an unmet need for the
treatment and therapeutic development of neurological disorders. The limiting factors for …

Somites are spherical aggregations of mesodermal cells located on either sides of neural
tube and are differentiated into sclerotome and dermomyotome. Notochord as an axial …

In the past few decades, embryonic stem cells (ESCs) were of great interest as a model
system for studying early developmental processes and because of their potential …

The cornea is the outermost layer of human eye and is an important part of the ocular light
path. The cornea is medically significant as corneal diseases account for 25% of blindness …