Genetic variants and type 2 diabetes in India: a systematic review and meta-analysis of associated polymorphisms in case-control studies

L Rathod, S Khan, S Mishra, D Das, K Bora… - The Lancet Regional …, 2025 - thelancet.com
Background India, with the largest population and second-highest type 2 diabetes mellitus
(T2DM) prevalence, presents a unique genetic landscape. This study explores the genetic …

The Multifaceted Role of the Polyphenol Curcumin: A Focus on Type 2 Diabetes Mellitus

R Campagna, M Cecati, A Vignini - Current Diabetes Reviews, 2024 - benthamdirect.com
Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disorder characterized by chronic
hyperglycemia, which often co-exists with other metabolic impairments. This condition can …

[HTML][HTML] Association Study of CACNA1D, KCNJ11, KCNQ1, and CACNA1E Single-Nucleotide Polymorphisms with Type 2 Diabetes Mellitus

JD Díaz-García, M Leyva-Leyva… - International Journal of …, 2024 - mdpi.com
Type 2 diabetes mellitus (T2DM) is a complex chronic disease characterized by decreased
insulin secretion and the development of insulin resistance. Previous genome-wide …

[HTML][HTML] Metabolic biomarkers in adults with type 2 diabetes: the role of PPAR-γ2 and PPAR-β/δ polymorphisms

SA Reza-López, S González-Gurrola… - Biomolecules, 2023 - mdpi.com
Glucose and lipid metabolism regulation by the peroxisome proliferator-activated receptors
(PPARs) has been extensively reported. However, the role of their polymorphisms remains …

Emerging role of hsa_circ_0000652, hsa-miR-21, SMAD2, and Foxo1 in type 2 diabetes mellitus pathogenesis

A Mostafa, A Abusree, RTM Hassanien, H Mahfouz… - Human Gene, 2025 - Elsevier
Background Diabetes mellitus (DM) is considered a metabolic disorder widely distributed
worldwide. Optimal options of treatment and their related mechanisms are still unclear …

[HTML][HTML] Genetic Predisposition to Prediabetes in the Kazakh Population

G Svyatova, G Berezina, A Murtazaliyeva… - Current Issues in …, 2024 - mdpi.com
The aim of this study was to conduct a comparative analysis of the population frequencies of
the minor allele of polymorphic variants in the genes TCF7L2 (rs7903146) and PPARG …

Managing drug therapy-related problems and assessment of chronic diabetic wounds

MIMS Mahendran, V Gopalakrishnan… - Current Medical …, 2024 - Taylor & Francis
Type 2 diabetes mellitus (T2DM), responsible for most diabetes cases recorded worldwide,
increases the risk of chronic wounds and amputation. Patients with T2DM appear to be more …

Transcriptome-driven Health-status Transversal-predictor Analysis (THTA) using the PBMC transcriptome for health, food, microbiome and disease markers for …

T Todt, I van Bussel, L Afmann, L Brennan, D Ivanova… - medRxiv, 2024 - medrxiv.org
We developed a novel machine-learning artificial intelligence (AI) approach to predict
general health and food-intake parameters named Transcriptome-driven Health-status …

Uncovering Key Features of Individuals Who Benefit from Polygenic Risk Scores in Prostate Cancer Prediction

A Hornback, M Isgut, A Jaishankar, H Sathu… - Proceedings of the 15th …, 2024 - dl.acm.org
Prostate cancer is the most common cancer in men in the United States, with almost 300,000
new cases expected in 2024. While certain non-genetic (NG) factors, such as diet, can be …

Unraveling the molecular crossroads: T2DM and Parkinson's disease interactions.

T LIU, X KONG, J WEI - Biocell, 2024 - search.ebscohost.com
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by persistent
hyperglycemia. In recent times, an elevated risk of Parkinson's disease (PD) development …