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Genetic variants and type 2 diabetes in India: a systematic review and meta-analysis of associated polymorphisms in case-control studies
L Rathod, S Khan, S Mishra, D Das, K Bora… - The Lancet Regional …, 2025 - thelancet.com
Background India, with the largest population and second-highest type 2 diabetes mellitus
(T2DM) prevalence, presents a unique genetic landscape. This study explores the genetic …
(T2DM) prevalence, presents a unique genetic landscape. This study explores the genetic …
The Multifaceted Role of the Polyphenol Curcumin: A Focus on Type 2 Diabetes Mellitus
Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disorder characterized by chronic
hyperglycemia, which often co-exists with other metabolic impairments. This condition can …
hyperglycemia, which often co-exists with other metabolic impairments. This condition can …
[HTML][HTML] Association Study of CACNA1D, KCNJ11, KCNQ1, and CACNA1E Single-Nucleotide Polymorphisms with Type 2 Diabetes Mellitus
JD Díaz-García, M Leyva-Leyva… - International Journal of …, 2024 - mdpi.com
Type 2 diabetes mellitus (T2DM) is a complex chronic disease characterized by decreased
insulin secretion and the development of insulin resistance. Previous genome-wide …
insulin secretion and the development of insulin resistance. Previous genome-wide …
[HTML][HTML] Metabolic biomarkers in adults with type 2 diabetes: the role of PPAR-γ2 and PPAR-β/δ polymorphisms
SA Reza-López, S González-Gurrola… - Biomolecules, 2023 - mdpi.com
Glucose and lipid metabolism regulation by the peroxisome proliferator-activated receptors
(PPARs) has been extensively reported. However, the role of their polymorphisms remains …
(PPARs) has been extensively reported. However, the role of their polymorphisms remains …
Emerging role of hsa_circ_0000652, hsa-miR-21, SMAD2, and Foxo1 in type 2 diabetes mellitus pathogenesis
A Mostafa, A Abusree, RTM Hassanien, H Mahfouz… - Human Gene, 2025 - Elsevier
Background Diabetes mellitus (DM) is considered a metabolic disorder widely distributed
worldwide. Optimal options of treatment and their related mechanisms are still unclear …
worldwide. Optimal options of treatment and their related mechanisms are still unclear …
[HTML][HTML] Genetic Predisposition to Prediabetes in the Kazakh Population
G Svyatova, G Berezina, A Murtazaliyeva… - Current Issues in …, 2024 - mdpi.com
The aim of this study was to conduct a comparative analysis of the population frequencies of
the minor allele of polymorphic variants in the genes TCF7L2 (rs7903146) and PPARG …
the minor allele of polymorphic variants in the genes TCF7L2 (rs7903146) and PPARG …
Managing drug therapy-related problems and assessment of chronic diabetic wounds
MIMS Mahendran, V Gopalakrishnan… - Current Medical …, 2024 - Taylor & Francis
Type 2 diabetes mellitus (T2DM), responsible for most diabetes cases recorded worldwide,
increases the risk of chronic wounds and amputation. Patients with T2DM appear to be more …
increases the risk of chronic wounds and amputation. Patients with T2DM appear to be more …
Transcriptome-driven Health-status Transversal-predictor Analysis (THTA) using the PBMC transcriptome for health, food, microbiome and disease markers for …
We developed a novel machine-learning artificial intelligence (AI) approach to predict
general health and food-intake parameters named Transcriptome-driven Health-status …
general health and food-intake parameters named Transcriptome-driven Health-status …
Uncovering Key Features of Individuals Who Benefit from Polygenic Risk Scores in Prostate Cancer Prediction
Prostate cancer is the most common cancer in men in the United States, with almost 300,000
new cases expected in 2024. While certain non-genetic (NG) factors, such as diet, can be …
new cases expected in 2024. While certain non-genetic (NG) factors, such as diet, can be …
Unraveling the molecular crossroads: T2DM and Parkinson's disease interactions.
T LIU, X KONG, J WEI - Biocell, 2024 - search.ebscohost.com
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by persistent
hyperglycemia. In recent times, an elevated risk of Parkinson's disease (PD) development …
hyperglycemia. In recent times, an elevated risk of Parkinson's disease (PD) development …