Prostate cancer has the highest prevalence of any nonskin cancer in the human body, with
similar likelihood of neoplastic foci found within the prostates of men around the world …

PURPOSE:: This is part 1 of a 2-part review. Research into the molecular mechanisms
underlying the various aspects of prostate cancer (PCa) requires the use of in vivo and in …

Here we report the characterization of an SV40 large-T antigen-immortalized stromal cell
line, WPMY-1, derived from the same prostate as our previously described epithelial cell …

A case of a 64-year-old man with bilateral diffuse uveal melanocytic proliferation is
presented. Bilateral diffuse uveal melanocytic proliferation is a rare paraneoplastic disorder …

Stromal cells are key regulators of growth and differentiation in the adult human prostate.
Alterations in the stroma are believed to initiate the development of benign prostatic …

We obtained a primary culture of prostatic cells through explantation from patients with
benign prostatic hyperplasia. Structural morphology, immunohistochemical staining, and …

In the present study we examined the expression and release of the extracellular matrix
glycoprotein fibronectin (FN) in a prostate cancer cell line (LNCaP) and in primary prostatic …

Stromal-epithelial interactions in the prostate gland are dependent on androgen regulation
of prostate stromal cells, yet little is known about androgen action in these cell types. Recent …

BACKGROUND Prostate stromal cells can be readily cultured in vitro. Are these proliferating
cells representative of stromal cells in situ? Since the expression of cell surface molecules …

BACKGROUND Stromal‐epithelial signaling plays an important role in prostate
development and cancer progression. Study of these interactions will be facilitated by the …