Cyclodextrin-based ocular drug delivery systems: A comprehensive review

Q Wang, A Zhang, L Zhu, X Yang, G Fang… - Coordination Chemistry …, 2023 - Elsevier
Cyclodextrin (CD), a class of cyclic oligosaccharides with an external hydrophilic surface
and a central hydrophobic cavity is recognized as a promising pharmaceutical excipient due …

[HTML][HTML] Cellulosic polymers for enhancing drug bioavailability in ocular drug delivery systems

B Gupta, V Mishra, S Gharat, M Momin, A Omri - Pharmaceuticals, 2021 - mdpi.com
One of the major impediments to drug development is low aqueous solubility and thus poor
bioavailability, which leads to insufficient clinical utility. Around 70–80% of drugs in the …

Lipid-based nanocarriers for ocular drug delivery: An updated review

B Das, AK Nayak, S Mallick - Journal of Drug Delivery Science and …, 2022 - Elsevier
Recent years have witnessed a boom in ocular nanomedicine research with a number of
lipid-based nanocarriers such as liposomes, niosomes, cubosomes, nanoemulsions, solid …

[HTML][HTML] Comparative evaluation of HET-CAM and ICE methods for objective assessment of ocular irritation caused by selected pesticide products

P Budai, É Kormos, I Buda, G Somody, J Lehel - Toxicology in vitro, 2021 - Elsevier
Eye irritation potency of pesticides (fungicides, herbicides, insecticides) was comparatively
tested by HET-CAM and ICE method. Based on the results of the tests the statistical analysis …

Aluminum neurotoxicity and autophagy: a mechanistic view

S Makhdoomi, S Ariafar, F Mirzaei… - Neurological …, 2023 - Taylor & Francis
It is strongly believed that aluminum is one of the insalubrious agents because of its
neurotoxicity effects and influences on amyloid β (Aβ) production and tau protein …

Fabrication of architectonic nanosponges for intraocular delivery of Brinzolamide: An insight into QbD driven optimization, in vitro characterization, and …

US Bagul, MV Nazirkar, AK Mane, SV Khot… - International Journal of …, 2024 - Elsevier
The intricate structure of the eye poses difficulties in drug targeting, which can be
surmounted with the help of nanoformulation strategies. With this view, brinzolamide …

[HTML][HTML] Nanomedicine in glaucoma treatment; Current challenges and future perspectives

H Iqbal, A Razzaq, D Zhou, J Lou, R **ao, F Lin… - Materials Today Bio, 2024 - Elsevier
Glaucoma presents a significant global health concern and affects millions of individuals
worldwide and predicted a high increase in prevalence of about 111 million by 2040. The …

[HTML][HTML] Innovations in Nanoemulsion Technology: Enhancing Drug Delivery for Oral, Parenteral, and Ophthalmic Applications

S Jacob, FS Kather, SHS Boddu, J Shah, AB Nair - Pharmaceutics, 2024 - mdpi.com
Nanoemulsions (NEs) are submicron-sized heterogeneous biphasic liquid systems
stabilized by surfactants. They are physically transparent or translucent, optically isotropic …

Overview of processed excipients in ocular drug delivery: Opportunities so far and bottlenecks

S Ashique, N Mishra, S Mohanto, BHJ Gowda, S Kumar… - Heliyon, 2024 - cell.com
Ocular drug delivery presents a unique set of challenges owing to the complex anatomy and
physiology of the eye. Processed excipients have emerged as crucial components in …

Nanoemulsification of Rose (Rosa damascena) Essential Oil: Characterization, Anti‐Salmonella, In Vitro Cytotoxicity to Cancer Cells, and Advantages in Sheep Meat …

I Saffari, A Motallebi Moghanjoghi… - Journal of Food …, 2023 - Wiley Online Library
Nowadays, consumers are pushing for the use of natural preservatives such as essential
oils (EOs) in the fresh and processed foods, including meat. However, this action is related …