Cu (I)-catalyzed click chemistry in glycoscience and their diverse applications
Copper (I)-catalyzed 1, 3-dipolar cycloaddition between organic azides and terminal
alkynes, commonly known as CuAAC or click chemistry, has been identified as one of the …
alkynes, commonly known as CuAAC or click chemistry, has been identified as one of the …
Chemically modified and conjugated antimicrobial peptides against superbugs
Antimicrobial resistance (AMR) is one of the greatest threats to human health that, by 2050,
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …
Cu-catalyzed click reaction in carbohydrate chemistry
Cu (I)-catalyzed azide–alkyne 1, 3-dipolar cycloaddition (CuAAC), popularly known as the
“click reaction”, serves as the most potent and highly dependable tool for facile construction …
“click reaction”, serves as the most potent and highly dependable tool for facile construction …
A comprehensive review of glycosylated bacterial natural products
A systematic analysis of all naturally-occurring glycosylated bacterial secondary metabolites
reported in the scientific literature up through early 2013 is presented. This comprehensive …
reported in the scientific literature up through early 2013 is presented. This comprehensive …
Click chemistry reactions in medicinal chemistry: Applications of the 1, 3‐dipolar cycloaddition between azides and alkynes
In recent years, there has been an ever‐increasing need for rapid reactions that meet the
three main criteria of an ideal synthesis: efficiency, versatility, and selectivity. Such reactions …
three main criteria of an ideal synthesis: efficiency, versatility, and selectivity. Such reactions …
Biosynthesis of nonribosomal peptides
R Finking, MA Marahiel - Annu. Rev. Microbiol., 2004 - annualreviews.org
▪ Abstract Bacteria and fungi use large multifunctional enzymes, the so-called nonribosomal
peptide synthetases (NRPSs), to produce peptides of broad structural and biological activity …
peptide synthetases (NRPSs), to produce peptides of broad structural and biological activity …
Synthesizing ginsenoside Rh2 in Saccharomyces cerevisiae cell factory at high-efficiency
Synthetic biology approach has been frequently applied to produce plant rare bioactive
compounds in microbial cell factories by fermentation. However, to reach an ideal …
compounds in microbial cell factories by fermentation. However, to reach an ideal …
Glycopeptide and lipoglycopeptide antibiotics
D Kahne, C Leimkuhler, W Lu, C Walsh - Chemical reviews, 2005 - ACS Publications
Vancomycin and teicoplanin are the two glycopeptide antibiotics that are used clinically, and
the emergence of resistance to them poses a serious threat to human health. Some …
the emergence of resistance to them poses a serious threat to human health. Some …
Glycosyltransferases: mechanisms and applications in natural product development
DM Liang, JH Liu, H Wu, BB Wang, HJ Zhu… - Chemical Society …, 2015 - pubs.rsc.org
Glycosylation reactions mainly catalyzed by glycosyltransferases (Gts) occur almost
everywhere in the biosphere, and always play crucial roles in vital processes. In order to …
everywhere in the biosphere, and always play crucial roles in vital processes. In order to …
[KİTAP][B] Anticancer agents from natural products
GM Cragg, DGI Kingston, DJ Newman - 2005 - taylorfrancis.com
Plants, marine organisms, and microorganisms have evolved complex chemical defense
and signaling systems that are designed to protect them from predators and provide other …
and signaling systems that are designed to protect them from predators and provide other …