Recent developments in PET instrumentation

H Peng, C S. Levin - Current pharmaceutical biotechnology, 2010 - benthamdirect.com
Positron emission tomography (PET) is used in the clinic and in vivo small animal research
to study molecular processes associated with diseases such as cancer, heart disease, and …

[PDF][PDF] Advances in preclinical PET instrumentation

M Amirrashedi, H Zaidi, MR Ay - PET clinics, 2020 - Elsevier
PET imaging technology is gaining momentum as a versatile and irreplaceable research
tool for a wide variety of applications in biomedical research due to gleaning a wealth of …

Performance of a high-resolution depth-encoding PET detector module using linearly-graded SiPM arrays

J Du, X Bai, A Gola, F Acerbi, A Ferri… - Physics in Medicine …, 2018 - iopscience.iop.org
The goal of this study was to exploit the excellent spatial resolution characteristics of a
position-sensitive silicon photomultiplier (SiPM) and develop a high-resolution depth-of …

Performance comparison of dual-ended readout depth-encoding PET detectors based on BGO and LYSO crystals

J Du, G Ariño-Estrada, X Bai… - Physics in Medicine & …, 2020 - iopscience.iop.org
The performance of dual-ended readout depth-encoding positron emission tomography
(PET) detectors based on bismuth germanate (BGO) coupled to silicon photomultipliers …

H2RSPET: a 0.5 mm resolution high-sensitivity small-animal PET scanner, a simulation study

Y Lai, Q Wang, S Zhou, Z ** a total-body small-animal PET system with a high spatial
resolution of∼ 0.5 mm and a high sensitivity> 10% for mouse/rat studies, we simulated four …

Detector block performance based on a monolithic LYSO crystal using a novel signal multiplexing method

A González-Montoro, F Sánchez, R Martí… - Nuclear Instruments and …, 2018 - Elsevier
Organ dedicated PET devices provide improved imaging performance when compared to
whole body systems. The present study summarizes the test carried out to study a new …

Tapered LSO arrays for small animal PET

Y Yang, SS James, Y Wu, H Du, J Qi… - Physics in Medicine …, 2010 - iopscience.iop.org
By using detectors with good depth encoding accuracy (∼ 2 mm), an animal PET scanner
can be built with a small ring diameter and thick crystals to simultaneously obtain high …

Design and evaluation of gapless curved scintillator arrays for simultaneous high-resolution and high-sensitivity brain PET

J Du, X Bai, CC Liu, J Qi… - Physics in Medicine & …, 2019 - iopscience.iop.org
Brain PET scanners that simultaneously provide high-resolution across the field-of-view and
high-sensitivity can be constructed using detectors based on SiPM arrays coupled to both …

A depth-encoding PET detector for high resolution PET using 1 mm SiPMs

J Du, X Bai, SR Cherry - Physics in Medicine & Biology, 2020 - iopscience.iop.org
A dual-ended readout PET detector based on two Hamamatsu 16× 16 arrays of 1× 1 mm 2
SiPMs coupled to both ends of a 25× 25 array of 0.69× 0.69× 20 mm 3 polished LYSOs was …

Depth of interaction determination in monolithic scintillator with double side SiPM readout

M Morrocchi, G Ambrosi, MG Bisogni, F Bosi, M Boretto… - EJNMMI physics, 2017 - Springer
Background Monolithic scintillators read out by arrays of photodetectors represent a
promising solution to obtain high spatial resolution and the depth of interaction (DOI) of the …