Sexually transmitted infections and female reproductive health

OT Van Gerwen, CA Muzny, JM Marrazzo - Nature microbiology, 2022 - nature.com
Women are disproportionately affected by sexually transmitted infections (STIs) throughout
life. In addition to their high prevalence in women, STIs have debilitating effects on female …

Role of vaginal microbiota dysbiosis in gynecological diseases and the potential interventions

Y Han, Z Liu, T Chen - Frontiers in microbiology, 2021 - frontiersin.org
Vaginal microbiota dysbiosis, characterized by the loss of Lactobacillus dominance and
increase of microbial diversity, is closely related to gynecological diseases; thus …

Strategies for prevention and treatment of Trichomonas vaginalis infections

K Bouchemal, C Bories, PM Loiseau - Clinical microbiology …, 2017 - Am Soc Microbiol
The last estimated annual incidence of Trichomonas vaginalis worldwide exceeds that of
chlamydia and gonorrhea combined. This critical review updates the state of the art on …

Gardnerella and vaginal health: the truth is out there

AS Rosca, J Castro, LGV Sousa… - FEMS microbiology …, 2020 - academic.oup.com
The human vagina is a dynamic ecosystem in which homeostasis depends on mutually
beneficial interactions between the host and their microorganisms. However, the vaginal …

Neutrophils kill the parasite Trichomonas vaginalis using trogocytosis

F Mercer, SH Ng, TM Brown, G Boatman… - PLoS biology, 2018 - journals.plos.org
T. vaginalis, a human-infective parasite, causes the most common nonviral sexually
transmitted infection (STI) worldwide and contributes to adverse inflammatory disorders. The …

Clinical and laboratory testing for Trichomonas vaginalis infection

B Van Der Pol - Journal of clinical microbiology, 2016 - Am Soc Microbiol
Trichomonas vaginalis infection is highly prevalent in the United States and worldwide.
Traditional clinical diagnostic methods fail to identify more than half of these infections that, if …

Guidelines for the purification and characterization of extracellular vesicles of parasites

C Fernandez‐Becerra, P Xander… - Journal of …, 2023 - Wiley Online Library
Parasites are responsible for the most neglected tropical diseases, affecting over a billion
people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible …

[HTML][HTML] Chitosan-based systems aimed at local application for vaginal infections

VHS Araujo, MPC de Souza, GC Carvalho… - Carbohydrate …, 2021 - Elsevier
Vaginal administration is a promising route for the local treatment of infectious vaginal
diseases since it can bypass the first-pass metabolism, drug interactions, and adverse …

Establishment and application of a CRISPR-Cas12a-based RPA-LFS and fluorescence for the detection of Trichomonas vaginalis

S Li, X Wang, Y Yu, S Cao, J Liu, P Zhao, J Li… - Parasites & vectors, 2022 - Springer
Abstract Background Infection with Trichomonas vaginalis can lead to cervicitis, urethritis,
pelvic inflammatory disease, prostatitis and perinatal complications and increased risk of …

Viruses of protozoan parasites and viral therapy: Is the time now right?

P Barrow, JC Dujardin, N Fasel, AD Greenwood… - Virology journal, 2020 - Springer
Infections caused by protozoan parasites burden the world with huge costs in terms of
human and animal health. Most parasitic diseases caused by protozoans are neglected …