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Computational coherent Raman scattering imaging: breaking physical barriers by fusion of advanced instrumentation and data science
Coherent Raman scattering (CRS) microscopy is a chemical imaging modality that provides
contrast based on intrinsic biomolecular vibrations. To date, endeavors on instrumentation …
contrast based on intrinsic biomolecular vibrations. To date, endeavors on instrumentation …
Recent Progress in Deep Learning for Improving Coherent Anti‐Stokes Raman Scattering Microscopy
B Yao, F Lin, Z Luo, Q Chen, D Lin… - Laser & Photonics …, 2024 - Wiley Online Library
Abstract Coherent anti‐Stokes Raman scattering (CARS) microscopy is a powerful label‐
free imaging technique that leverages biomolecular vibrations and is widely used in different …
free imaging technique that leverages biomolecular vibrations and is widely used in different …
Full-spectrum CARS microscopy of cells and tissues with ultrashort white-light continuum pulses
Coherent anti-Stokes Raman scattering (CARS) microscopy is an emerging nonlinear
vibrational imaging technique that delivers label-free chemical maps of cells and tissues. In …
vibrational imaging technique that delivers label-free chemical maps of cells and tissues. In …
Pulse-picking multimodal nonlinear optical microscopy
Nonlinear optical microscopy techniques can map chemical compositions in biological
samples in a label-free manner. Commonly used nonlinear optical processes for imaging …
samples in a label-free manner. Commonly used nonlinear optical processes for imaging …
Raman micro-spectroscopy reveals the spatial distribution of fumarate in cells and tissues
Aberrantly accumulated metabolites elicit intra-and inter-cellular pro-oncogenic cascades,
yet current measurement methods require sample perturbation/disruption and lack spatio …
yet current measurement methods require sample perturbation/disruption and lack spatio …
[HTML][HTML] Removing non-resonant background of CARS signal with generative adversarial network
Coherent anti-Stokes Raman scattering (CARS) microscopy requires the removal of non-
resonant background (NRB) to ensure spectral accuracy and quality. This study introduces a …
resonant background (NRB) to ensure spectral accuracy and quality. This study introduces a …
Simultaneous label-free autofluorescence multi-harmonic microscopy driven by the supercontinuum generated from a bulk nonlinear crystal
Nonlinear microscopy encompasses several imaging techniques that leverage laser
technology to probe intrinsic molecules of biological specimens. These native molecules …
technology to probe intrinsic molecules of biological specimens. These native molecules …
Label-free multimodal nonlinear optical microscopy reveals features of bone composition in pathophysiological conditions
Bone tissue features a complex microarchitecture and biomolecular composition, which
determine biomechanical properties. In addition to state-of-the-art technologies, innovative …
determine biomechanical properties. In addition to state-of-the-art technologies, innovative …
[HTML][HTML] Dual picosecond fast tunable optical parametric amplifier laser system for wide-field nonlinear optical microscopy
In the last decades, nonlinear optical microscopy techniques, such as two-Photon Excited
Fluorescence (2PEF), Sum Frequency Generation (SFG), and Hyperspectral Coherent Anti …
Fluorescence (2PEF), Sum Frequency Generation (SFG), and Hyperspectral Coherent Anti …
Estimation of biological variance in coherent Raman microscopy data of two cell lines using chemometrics
Broadband Coherent Anti-Stokes Raman Scattering (BCARS) is a valuable spectroscopic
imaging tool for visualizing cellular structures and lipid distributions in biomedical …
imaging tool for visualizing cellular structures and lipid distributions in biomedical …