The past 20 years have witnessed ever-growing evidence that the mechanical properties of
biological tissues, from nanoscale to macroscale dimensions, are fundamental for cellular …

Fast, high-resolution, non-destructive and quantitative characterization methods are needed
to develop materials with tailored properties at the nanoscale or to understand the …

Mechanobiology emerges at the crossroads of medicine, biology, biophysics and
engineering and describes how the responses of proteins, cells, tissues and organs to …

The atomic force microscope (AFM) is not only a tool to image the topography of solid
surfaces at high resolution. It can also be used to measure force-versus-distance curves …

Contractile myocytes provide a test of the hypothesis that cells sense their mechanical as
well as molecular microenvironment, altering expression, organization, and/or morphology …

Physical forces and mechanical properties have critical roles in cellular function, physiology
and disease. Over the past decade, atomic force microscopy (AFM) techniques have …

Mechanical properties of individual living cells are known to be closely related to the health
and function of the human body. Here, atomic force microscopy (AFM) indentation using a …

The cytoplasm is the largest part of the cell by volume and hence its rheology sets the rate at
which cellular shape changes can occur. Recent experimental evidence suggests that …

Aberrant extracellular matrix (ECM) assembly surrounding implanted biomaterials is the
hallmark of the foreign body response, in which implants become encapsulated in thick …

The growth of stem cells can be modulated by physical factors such as extracellular matrix
nanotopography. We hypothesize that nanotopography modulates cell behavior by …