N-Heterocyclic carbenes (NHCs) are unique Lewis basic catalysts that mediate various
organic transformations by means of polarity reversal. Although the scope of research on …

Much progress has been made in the development of methods to both create compounds
that contain C− F bonds and to functionalize C− F bonds. As such, C− F bonds are becoming …

Radical/radical cross-coupling reactions represent an efficient and straightforward approach
for the construction of chemical bonds and accordingly have drawn increasing attention over …

Three-component carboacylation of simple alkenes with readily available reagents is
challenging. Transition metal-catalysed intermolecular carboacylation works for alkenes with …

Direct synthesis of ketones from aldehydes features high atom-and step-economy. Yet, the
coupling of aldehydes with unactivated alkyl C (sp3)-H remains challenging. Herein, we …

There have been significant advancements in radical-mediated reactions through covalent-
based organocatalysis. Here, we present the generation of iminyl and amidyl radicals via N …

Abstract α‐Trifluoromethylated ketones have attracted significant attention as valuable
building blocks in organic synthesis. Such compounds are generally accessed through …

A Markovnikov-selective hydroacylation of alkenes has been achieved via the synergistic
merger cobalt, photoredox and N-heterocyclic carbene catalysis. The closely incorporated …

Herein, we report a mild, operationally simple, multicatalytic method for the synthesis of β, γ-
unsaturated ketones via allylic acylation of alkenes. Specifically, the method combines N …

The radical acylated difunctionalization of unsaturated carbon–carbon bonds, which
introduces acyl and other groups simultaneously, represents an attractive approach for the …