Polysaccharide‐based controlled release systems for therapeutics delivery and tissue engineering: from bench to bedside
Polysaccharides or polymeric carbohydrate molecules are long chains of monosaccharides
that are linked by glycosidic bonds. The naturally based structural materials are widely …
that are linked by glycosidic bonds. The naturally based structural materials are widely …
Polysaccharide-based nanoparticles for theranostic nanomedicine
Polysaccharides are natural biological molecules that have numerous advantages for
theranostics, the integrated approach of therapeutics and diagnostics. Their derivable …
theranostics, the integrated approach of therapeutics and diagnostics. Their derivable …
Metabolic reconstruction for metagenomic data and its application to the human microbiome
Microbial communities carry out the majority of the biochemical activity on the planet, and
they play integral roles in processes including metabolism and immune homeostasis in the …
they play integral roles in processes including metabolism and immune homeostasis in the …
Roles of proteoglycans and glycosaminoglycans in cancer development and progression
J Wei, M Hu, K Huang, S Lin, H Du - International journal of molecular …, 2020 - mdpi.com
The extracellular matrix (ECM) spatiotemporally controls cell fate; however, dysregulation of
ECM remodeling can lead to tumorigenesis and cancer development by providing favorable …
ECM remodeling can lead to tumorigenesis and cancer development by providing favorable …
The structure of glycosaminoglycans and their interactions with proteins
Glycosaminoglycans (GAGs) are important complex carbohydrates that participate in many
biological processes through the regulation of their various protein partners. Biochemical …
biological processes through the regulation of their various protein partners. Biochemical …
B cell and B cell-related pathways for novel cancer treatments
R Tokunaga, M Naseem, JH Lo, F Battaglin… - Cancer treatment …, 2019 - Elsevier
B cells are recognized as the main effector cells of humoral immunity which suppress tumor
progression by secreting immunoglobulins, promoting T cell response, and killing cancer …
progression by secreting immunoglobulins, promoting T cell response, and killing cancer …
Medical application of glycosaminoglycans: a review
A Köwitsch, G Zhou, T Groth - Journal of tissue engineering …, 2018 - Wiley Online Library
The characteristic molecular composition of the different glycosaminoglycans (GAGs) is
related to their role as structural components and regulators of a multitude of functions of …
related to their role as structural components and regulators of a multitude of functions of …
Cell-surface heparan sulfate proteoglycans as multifunctional integrators of signaling in cancer
Proteoglycans (PGs) represent a large proportion of the components that constitute the
extracellular matrix (ECM). They are a diverse group of glycoproteins characterized by a …
extracellular matrix (ECM). They are a diverse group of glycoproteins characterized by a …
Functions and clinical significance of mechanical tumor microenvironment: cancer cell sensing, mechanobiology and metastasis
H Zhou, M Wang, Y Zhang, Q Su, Z **e… - Cancer …, 2022 - Wiley Online Library
Dynamic and heterogeneous interaction between tumor cells and the surrounding
microenvironment fuels the occurrence, progression, invasion, and metastasis of solid …
microenvironment fuels the occurrence, progression, invasion, and metastasis of solid …
Breast cancer stem cells, EMT and therapeutic targets
S Kotiyal, S Bhattacharya - Biochemical and biophysical research …, 2014 - Elsevier
A small heterogeneous population of breast cancer cells acts as seeds to induce new tumor
growth. These seeds or breast cancer stem cells (BCSCs) exhibit great phenotypical …
growth. These seeds or breast cancer stem cells (BCSCs) exhibit great phenotypical …