Salivary secretion in health and disease

AML Pedersen, CE Sørensen… - Journal of oral …, 2018‏ - Wiley Online Library
Saliva is a complex fluid produced by 3 pairs of major salivary glands and by hundreds of
minor salivary glands. It comprises a large variety of constituents and physicochemical …

Influence of saliva on the oral microbiota

PD Marsh, T Do, D Beighton, DA Devine - Periodontology 2000, 2016‏ - Wiley Online Library
Saliva plays a major role in determining the composition and activity of the oral microbiota,
via a variety of mechanisms. Molecules, mainly from saliva, form a conditioning film on oral …

Salivary proteins and microbiota as biomarkers for early childhood caries risk assessment

AS Hemadi, R Huang, Y Zhou, J Zou - International journal of oral …, 2017‏ - nature.com
Early childhood caries (ECC) is a term used to describe dental caries in children aged 6
years or younger. Oral streptococci, such as Streptococcus mutans and Streptococcus …

New insights into the composition and functions of the acquired enamel pellicle

WL Siqueira, W Custodio… - Journal of dental …, 2012‏ - journals.sagepub.com
The acquired enamel pellicle (AEP) is a thin acellular film that forms on tooth surfaces upon
exposure to the oral environment. It consists predominantly of salivary proteins, but also …

Current state and challenges of the global outcomes of dental caries research in the meta-omics era

DG Moussa, P Ahmad, TA Mansour… - Frontiers in Cellular and …, 2022‏ - frontiersin.org
Despite significant healthcare advances in the 21st century, the exact etiology of dental
caries remains unsolved. The past two decades have witnessed a tremendous growth in our …

Salivary proteins as dental caries biomarkers: a systematic review

P Ahmad, A Hussain, A Carrasco-Labra… - Caries Research, 2022‏ - karger.com
Salivary proteins play an important role in repairing mechanisms of damaged tissues and
the maintenance of oral health. However, there is a dearth of information in the literature …

Saliva as a diagnostic tool for dental caries, periodontal disease and cancer: is there a need for more biomarkers?

MAR Buzalaf, AC Ortiz, TS Carvalho… - Expert review of …, 2020‏ - Taylor & Francis
Introduction: A biomarker is a biological indicator of normal or pathogenic processes.
Identification of biomarkers is useful for the prevention, diagnosis and prognosis of diseases …

[HTML][HTML] Histatin peptides: Pharmacological functions and their applications in dentistry

Z Khurshid, S Najeeb, M Mali, SF Moin, SQ Raza… - Saudi Pharmaceutical …, 2017‏ - Elsevier
There are many human oral antimicrobial peptides responsible for playing important roles
including maintenance, repairing of oral tissues (hard or soft) and defense against oral …

Stimulated and unstimulated saliva samples have significantly different bacterial profiles

S Gomar-Vercher, A Simón-Soro… - PloS one, 2018‏ - journals.plos.org
Epidemiological studies use saliva on a regular basis as a non-invasive and easy-to-take
sample, which is assumed to be a microbial representative of the oral cavity ecosystem …

The caries environment: saliva, pellicle, diet, and hard tissue ultrastructure

AT Hara, DT Zero - Dental Clinics, 2010‏ - dental.theclinics.com
An important starting place when discussing the caries environment is to accept that it is only
the biofilm-covered tooth surfaces that have the potential to develop caries lesions. The …