Point-of-care PCR assays for COVID-19 detection
Molecular diagnostics has been the front runner in the world's response to the COVID-19
pandemic. Particularly, reverse transcriptase-polymerase chain reaction (RT-PCR) and the …
pandemic. Particularly, reverse transcriptase-polymerase chain reaction (RT-PCR) and the …
Microfluidics for detection of exosomes and microRNAs in cancer: State of the art
Exosomes are small extracellular vesicles with sizes ranging from 30–150 nanometers that
contain proteins, lipids, mRNAs, microRNAs, and double-stranded DNA derived from the …
contain proteins, lipids, mRNAs, microRNAs, and double-stranded DNA derived from the …
[HTML][HTML] Biosensors as diagnostic tools in clinical applications
Nowadays, the development of new technological solutions in the medical field, in particular
biosensors, is a priority and a ground for great scientific and financial investment. From …
biosensors, is a priority and a ground for great scientific and financial investment. From …
Identification of clinically relevant biomarkers of epileptogenesis—a strategic roadmap
M Simonato, DV Agoston, A Brooks-Kayal… - Nature Reviews …, 2021 - nature.com
Onset of many forms of epilepsy occurs after an initial epileptogenic insult or as a result of an
identified genetic defect. Given that the precipitating insult is known, these epilepsies are, in …
identified genetic defect. Given that the precipitating insult is known, these epilepsies are, in …
Proteins and microRNAs are differentially expressed in tear fluid from patients with Alzheimer's disease
A Kenny, EM Jimenez-Mateos, MA Zea-Sevilla… - Scientific reports, 2019 - nature.com
Alzheimer's disease (AD) is characterized by a progressive loss of neurons and cognitive
functions. Therefore, early diagnosis of AD is critical. The development of practical and non …
functions. Therefore, early diagnosis of AD is critical. The development of practical and non …
Recent progress in microfluidics-based biosensing
Y Song, B Lin, T Tian, X Xu, W Wang, Q Ruan… - Analytical …, 2018 - ACS Publications
Biosensors are analytical devices or systems used to detect a specific target by converting
and amplifying a biomolecular recognition event to a dateable semiquantitative or …
and amplifying a biomolecular recognition event to a dateable semiquantitative or …
Dual-center, dual-platform microRNA profiling identifies potential plasma biomarkers of adult temporal lobe epilepsy
Background There are no blood-based molecular biomarkers of temporal lobe epilepsy
(TLE) to support clinical diagnosis. MicroRNAs are short noncoding RNAs with strong …
(TLE) to support clinical diagnosis. MicroRNAs are short noncoding RNAs with strong …
Biosensing on the centrifugal microfluidic lab-on-a-disc platform
Lab-on-a-Disc (LoaD) biosensors are increasingly a promising solution for many biosensing
applications. In the search for a perfect match between point-of-care (PoC) microfluidic …
applications. In the search for a perfect match between point-of-care (PoC) microfluidic …
Materials, assemblies and reaction systems under rotation
BA Grzybowski, YI Sobolev, O Cybulski… - Nature Reviews …, 2022 - nature.com
When liquids or solid materials rotate, they impart centrifugal and/or shear forces. This
Review surveys rotary devices and systems in which such forces control small-scale flows …
Review surveys rotary devices and systems in which such forces control small-scale flows …
Elevation of plasma tRNA fragments precedes seizures in human epilepsy
Transfer RNAs (tRNAs) are a major class of noncoding RNA. Stress-induced cleavage of
tRNA is highly conserved and results in tRNA fragments. Here, we found that specific tRNA …
tRNA is highly conserved and results in tRNA fragments. Here, we found that specific tRNA …