Background & Aims Little is known about differences in rates of fibrosis progression between
patients with nonalcoholic fatty liver (NAFL) vs nonalcoholic steatohepatitis (NASH). We …

Cirrhosis is defined as the histological development of regenerative nodules surrounded by
fibrous bands in response to chronic liver injury, which leads to portal hypertension and end …

We performed a multitiered, case-control association study of psoriasis in three independent
sample sets of white North American individuals (1,446 cases and 1,432 controls) with …

Continued elucidation of the mechanisms of hepatic fibrosis has yielded a comprehensive
and nuanced portrait of fibrosis progression and regression. The paradigm of hepatic …

Pancreatic stellate cells (PaSCs) are myofibroblast-like cells found in the areas of the
pancreas that have exocrine function. PaSCs are regulated by autocrine and paracrine …

Hepatitis C virus (HCV) infection remains a major global health burden. Hepatitis C causes
significant liver-related morbidity and mortality due to hepatic decompensation and …

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the
United States, and its prevalence is increasing worldwide. It currently affects approximately …

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the
United States and many other parts of the world. Its prevalence continues to rise—currently …

Hepatitis C virus (HCV) is an RNA virus that affects> 180 million individuals worldwide with a
high propensity for chronic infection. Children with HCV infection differ from adults in several …

Clinical factors such as age, gender, alcohol use, and age‐at‐infection influence the
progression to cirrhosis but cannot accurately predict the risk of develo** cirrhosis in …