Reactive oxygen species-mediated cardiac-reperfusion injury: mechanisms and therapies

F Bagheri, V Khori, AM Alizadeh, S Khalighfard… - Life Sciences, 2016 - Elsevier
Reperfusion injury is an inherent response to the restoration of blood flow after ischemia. It is
a complex process involving numerous mechanisms occurring in the intracellular and …

[HTML][HTML] Health position paper and redox perspectives on reactive oxygen species as signals and targets of cardioprotection

G Heusch, I Andreadou, R Bell, E Bertero, HE Botker… - Redox Biology, 2023 - Elsevier
The present review summarizes the beneficial and detrimental roles of reactive oxygen
species in myocardial ischemia/reperfusion injury and cardioprotection. In the first part, the …

The prolyl 4-hydroxylase inhibitor GSK360A decreases post-stroke brain injury and sensory, motor, and cognitive behavioral deficits

J Zhou, J Li, DM Rosenbaum, J Zhuang, C Poon… - PLoS …, 2017 - journals.plos.org
There is interest in pharmacologic preconditioning for end-organ protection by targeting the
HIF system. This can be accomplished by inhibition of prolyl 4-hydroxylase (PHD). GSK360A …

Activation of endocannabinoid receptor 2 as a mechanism of propofol pretreatment‐induced cardioprotection against ischemia‐reperfusion injury in rats

HJ Sun, Y Lu, HW Wang, H Zhang… - Oxidative medicine …, 2017 - Wiley Online Library
Propofol pretreatment before reperfusion, or propofol conditioning, has been shown to be
cardioprotective, while its mechanism is unclear. The current study investigated the roles of …

Кардиопротективные эффекты ишемического кондиционирования: современные представления о механизмах, экспериментальные подтверждения …

АЕ Баутин, ЛИ Карпова… - Трансляционная …, 2016 - transmed.almazovcentre.ru
Аннотация Ишемическое кондиционирование предполагает индукцию
органопротекции при выполнении коротких эпизодов ишемии-реперфузии до или …

Effects of ischaemic postconditioning in aortic valve replacement: a multicenter randomized controlled trial

ML Kaljusto, A Bautin, Ø Jakobsen… - European Journal of …, 2022 - academic.oup.com
OBJECTIVES The effect of ischaemic postconditioning (IPost) on postcardioplegic cardiac
function is not known. We hypothesized that IPost was cardioprotective in adult patients …

Acute inhibition of monoamine oxidase and ischemic preconditioning in isolated rat hearts: interference with postischemic functional recovery but no effect on infarct …

MD Dănilă, AI Privistirescu, SN Mirica… - Canadian Journal of …, 2015 - cdnsciencepub.com
Monoamine oxidases (MAOs) have recently emerged as important mitochondrial sources of
oxidative stress in the cardiovascular system. Generation of reactive oxygen species during …

Сердечный тропонин I для оценки повреждения миокарда и прогнозирования осложнений у кардиохирургических пациентов

ТА Шешурина, ВВ Дорофейков… - Медицинский …, 2021 - med-alphabet.com
Аннотация В исследовании проведен анализ уровня тропонина I в крови у пациентов с
ишемической болезнью сердца после аортокоронарного шунтирования в сравнении с …

缺血性脑血管病患者血清 MMP-8 和 IL-6 水**与颈动脉粥样硬化的关系.

徐畅, 王晓梅, 朱刚, 宋倩… - Progress in Modern …, 2015 - search.ebscohost.com
摘要目的: 分析缺血性脑血管病患者血清MMP-8 和IL-6 的表达水**与颈动脉粥样硬化斑块稳定
性的关系. 方法: 选取2013 年5 月至2014 年10 月我院收治的80 例缺血性脑血管病患者作为 …

Efeito cardioprotetor do timol em corações de ratos submetidos à lesão de isquemia e reperfusão

JF Santos - 2016 - ri.ufs.br
RESUMO O infarto agudo do miocárdio ocorre quando há diminuição do suprimento
sanguíneo no miocárdio promovendo queda do aporte de Oxigênio (O2). É uma das …