Primary immune thrombocytopenia: novel insights into pathophysiology and disease management
A Singh, G Uzun, T Bakchoul - Journal of Clinical Medicine, 2021 - mdpi.com
Immune thrombocytopenia (ITP) is an autoimmune disorder defined by a significantly
reduced number of platelets in blood circulation. Due to low levels of platelets, ITP is …
reduced number of platelets in blood circulation. Due to low levels of platelets, ITP is …
The immune thrombocytopenia paradox: Should we be concerned about thrombosis in ITP?
Despite the predisposition to bleeding, patients with immune thrombocytopenia (ITP) may
also have an increased risk of arterial and venous thrombosis, which can contribute to …
also have an increased risk of arterial and venous thrombosis, which can contribute to …
Platelets in ITP: victims in charge of their own fate?
VS Nelson, ATC Jolink, SN Amini, JJ Zwaginga… - Cells, 2021 - mdpi.com
Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder. The
pathophysiological mechanisms leading to low platelet levels in ITP have not been resolved …
pathophysiological mechanisms leading to low platelet levels in ITP have not been resolved …
Pathophysiology of autoimmune thrombocytopenia: current insight with a focus on thrombopoiesis
I Marini, T Bakchoul - Hämostaseologie, 2019 - thieme-connect.com
Immune thrombocytopenia (ITP) is an autoimmune disease characterized by a significant
reduction in the number of circulating platelets which is frequently associated with bleeding …
reduction in the number of circulating platelets which is frequently associated with bleeding …
Apoptosis in megakaryocytes: Safeguard and threat for thrombopoiesis
S Yang, L Wang, Y Wu, A Wu, F Huang… - Frontiers in …, 2023 - frontiersin.org
Platelets, generated from precursor megakaryocytes (MKs), are central mediators of
hemostasis and thrombosis. The process of thrombopoiesis is extremely complex, regulated …
hemostasis and thrombosis. The process of thrombopoiesis is extremely complex, regulated …
[HTML][HTML] Desialylation and Apoptosis in Immune Thrombocytopenia: Implications for Pathogenesis and Treatment
SS Zheng, JS Perdomo - Current Issues in Molecular Biology, 2024 - mdpi.com
Immune thrombocytopenia (ITP) is an autoimmune disease in which platelet autoantibodies
play a significant role in its pathogenesis. Regulatory T cell dysfunction and T cell-mediated …
play a significant role in its pathogenesis. Regulatory T cell dysfunction and T cell-mediated …
The extensive regulation of microRNA in immune thrombocytopenia
Y Zhao, S Cui, Y Wang, R Xu - Clinical and Applied …, 2022 - journals.sagepub.com
MicroRNA (miRNA) is a small, single-stranded, non-coding RNA molecule that plays a
variety of key roles in different biological processes through post-transcriptional regulation of …
variety of key roles in different biological processes through post-transcriptional regulation of …
Insights on chronic immune thrombocytopenia pathogenesis: a bench to bedside update
JC Jaime-Pérez, EM Ramos-Dávila… - Blood Reviews, 2021 - Elsevier
Immune thrombocytopenia (ITP) is a heterogeneous disease with an unpredictable course.
Chronicity can develop in up to two-thirds of adults and 20–25% of children, representing a …
Chronicity can develop in up to two-thirds of adults and 20–25% of children, representing a …
Significant reductions in apoptosis-related proteins (HSPA6, HSPA8, ITGB3, YWHAH, and PRDX6) are involved in immune thrombocytopenia
S Liu, D Yuan, RJ Sun, J Zhu, N Shan - Journal of Thrombosis and …, 2021 - Springer
To investigate differences in the expression of plasma proteins in immune thrombocytopenia
(ITP) and normal control groups, bone marrow samples were collected from 20 active ITP …
(ITP) and normal control groups, bone marrow samples were collected from 20 active ITP …
The intestinal flora: The key to unraveling heterogeneity in immune thrombocytopenia?
Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder characterized by
enhanced platelet destruction and impaired platelet production, due to a loss of immune …
enhanced platelet destruction and impaired platelet production, due to a loss of immune …