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Current strategies for brain drug delivery
X Dong - Theranostics, 2018 - pmc.ncbi.nlm.nih.gov
The blood-brain barrier (BBB) has been a great hurdle for brain drug delivery. The BBB in
healthy brain is a diffusion barrier essential for protecting normal brain function by impeding …
healthy brain is a diffusion barrier essential for protecting normal brain function by impeding …
Designing delivery systems for functional ingredients by protein/polysaccharide interactions
Background Designing delivery systems (or called encapsulation systems) for functional
ingredients recently has received growing interest in the food industry, which aims to …
ingredients recently has received growing interest in the food industry, which aims to …
Drug delivery to the brain across the blood–brain barrier using nanomaterials
A major obstacle facing brain diseases such as Alzheimer's disease, multiple sclerosis,
brain tumors, and strokes is the blood–brain barrier (BBB). The BBB prevents the passage of …
brain tumors, and strokes is the blood–brain barrier (BBB). The BBB prevents the passage of …
Effective and targeted human orthotopic glioblastoma xenograft therapy via a multifunctional biomimetic nanomedicine
Glioblastoma multiforme (GBM) is a fatal central nervous system tumor without effective
treatment. Chemotherapeutic agents are mainstays in the treatment of glioblastoma …
treatment. Chemotherapeutic agents are mainstays in the treatment of glioblastoma …
[HTML][HTML] Bio-based and bio-inspired adhesives from animals and plants for biomedical applications
With the “many-headed” slime mold Physarum polycelphalum having been voted the
unicellular organism of the year 2021 by the German Society of Protozoology, we are …
unicellular organism of the year 2021 by the German Society of Protozoology, we are …
Strategies facilitating the permeation of nanoparticles through blood-brain barrier: An insight towards the development of brain-targeted drug delivery system
The blood-brain barrier (BBB) is a membrane barrier considered one of the most crucial
protective architectures in the central nervous system (CNS). Its presence acts as a hurdle …
protective architectures in the central nervous system (CNS). Its presence acts as a hurdle …
Targeting the blood-brain barrier for the delivery of stroke therapies
A variety of neuroprotectants have shown promise in treating ischemic stroke, yet their
delivery to the brain remains a challenge. The endothelial cells lining the blood-brain barrier …
delivery to the brain remains a challenge. The endothelial cells lining the blood-brain barrier …
[HTML][HTML] Challenges and opportunities for improving the druggability of natural product: Why need drug delivery system?
P Tang, T Shen, H Wang, R Zhang, X Zhang… - Biomedicine & …, 2023 - Elsevier
Bioactive natural products (BNPs) are the marrow of medicinal plants, which are the
secondary metabolites of organisms and have been the most famous drug discovery …
secondary metabolites of organisms and have been the most famous drug discovery …
Ozone-induced neurotoxicity: In vitro and in vivo evidence
A Singh, S Suresh, C Vellapandian - Ageing Research Reviews, 2023 - Elsevier
Together with cities in higher-income nations, it is anticipated that the real global ozone is
rising in densely populated areas of Asia and Africa. This review aims to discuss the …
rising in densely populated areas of Asia and Africa. This review aims to discuss the …
Carbohydrate‐based nanomaterials for biomedical applications
Carbohydrates are abundant biomolecules, with a strong tendency to form supramolecular
networks. A host of carbohydrate‐based nanomaterials have been exploited for biomedical …
networks. A host of carbohydrate‐based nanomaterials have been exploited for biomedical …