Muscle atrophy in patients with Type 2 Diabetes Mellitus: roles of inflammatory pathways, physical activity and exercise

BD Perry, MK Caldow… - Exercise …, 2016 - pmc.ncbi.nlm.nih.gov
Muscle atrophy is caused by an imbalance in contractile protein synthesis and degradation
which can be triggered by various conditions including Type 2 Diabetes Mellitus (T2DM) …

Exosomes-regulated lipid metabolism in tumorigenesis and cancer progression

L Ye, Y Li, S Zhang, J Wang, B Lei - Cytokine & Growth Factor Reviews, 2023 - Elsevier
Increasing evidence highlights the role of lipid metabolism in tumorigenesis and tumor
progression. Targeting the processes of lipid metabolism, including lipogenesis, lipid …

Resistance exercise intensity is correlated with attenuation of HbA1c and insulin in patients with type 2 diabetes: a systematic review and meta-analysis

Y Liu, W Ye, Q Chen, Y Zhang, CH Kuo… - International journal of …, 2019 - mdpi.com
We investigated the influence of resistance exercise (RE) with different intensities on HbA1c,
insulin and blood glucose levels in patients with type 2 diabetes (T2D). Diabetes trials that …

Resistance training to improve type 2 diabetes: working toward a prescription for the future

DH Pesta, RLS Goncalves, AK Madiraju, B Strasser… - Nutrition & …, 2017 - Springer
The prevalence of type 2 diabetes (T2D) is rapidly increasing, and effective strategies to
manage and prevent this disease are urgently needed. Resistance training (RT) promotes …

[HTML][HTML] The role of raptor in the mechanical load-induced regulation of mTOR signaling, protein synthesis, and skeletal muscle hypertrophy

JS You, RM McNally, BL Jacobs, RE Privett… - The FASEB …, 2018 - pmc.ncbi.nlm.nih.gov
It is well known that an increase in mechanical loading can induce skeletal muscle
hypertrophy, and a long standing model in the field indicates that mechanical loads induce …

Exercise training improves motor skill learning via selective activation of mTOR

K Chen, Y Zheng, J Wei, H Ouyang, X Huang… - Science …, 2019 - science.org
Physical exercise improves learning and memory, but little in vivo evidence has been
provided to illustrate the molecular mechanisms. Here, we show that chronic treadmill …

Role of mTORC1 in mechanically induced increases in translation and skeletal muscle mass

CA Goodman - Journal of applied physiology, 2019 - journals.physiology.org
Skeletal muscle mass is, in part, regulated by the rate of mRNA translation (ie, protein
synthesis). The conserved serine/threonine kinase, mTOR (the mammalian/mechanistic …

Exercise and the control of muscle mass in human

M Francaux, L Deldicque - Pflügers Archiv-European Journal of Physiology, 2019 - Springer
During the course of life, muscle mass undergoes many changes in terms of quantity and
quality. Skeletal muscle is a dynamic tissue able to hypertrophy or atrophy according to …

Bone and skeletal muscle: Key players in mechanotransduction and potential overlap** mechanisms

CA Goodman, TA Hornberger, AG Robling - Bone, 2015 - Elsevier
The development and maintenance of skeletal muscle and bone mass is critical for
movement, health and issues associated with the quality of life. Skeletal muscle and bone …

Exercise-induced skeletal muscle signaling pathways and human athletic performance

DM Camera, WJ Smiles, JA Hawley - Free Radical Biology and Medicine, 2016 - Elsevier
Skeletal muscle is a highly malleable tissue capable of altering its phenotype in response to
external stimuli including exercise. This response is determined by the mode,(endurance …