meso-Methyl BODIPY Photocages: Mechanisms, Photochemical Properties, and Applications

P Shrestha, D Kand, R Weinstain… - Journal of the American …, 2023‏ - ACS Publications
meso-methyl BODIPY photocages have recently emerged as an exciting new class of
photoremovable protecting groups (PPGs) that release leaving groups upon absorption of …

Visible-to-NIR-light activated release: from small molecules to nanomaterials

R Weinstain, T Slanina, D Kand, P Klan - Chemical reviews, 2020‏ - ACS Publications
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …

Taking phototherapeutics from concept to clinical launch

BM Vickerman, EM Zywot, TK Tarrant… - Nature Reviews …, 2021‏ - nature.com
More than four decades have passed since the first example of a light-activated (caged)
compound was described. In the intervening years, a large number of light-responsive …

Light: a magical tool for controlled drug delivery

Y Tao, HF Chan, B Shi, M Li… - Advanced Functional …, 2020‏ - Wiley Online Library
Light is a particularly appealing tool for on‐demand drug delivery due to its noninvasive
nature, ease of application, and exquisite temporal and spatial control. Great progress is …

Carbon-Dot-Decorated Carbon Nitride Nanoparticles for Enhanced Photodynamic Therapy against Hypoxic Tumor via Water Splitting

DW Zheng, B Li, CX Li, JX Fan, Q Lei, C Li, Z Xu… - ACS …, 2016‏ - ACS Publications
Hypoxia, a typical feature of solid tumors, remarkably restricts the efficiency of photodynamic
therapy (PDT). Here, a carbon nitride (C3N4)-based multifunctional nanocomposite (PCCN) …

Gas-mediated cancer bioimaging and therapy

L Chen, SF Zhou, L Su, J Song - ACS nano, 2019‏ - ACS Publications
Gas-involving cancer theranostics have attracted considerable attention in recent years due
to their high therapeutic efficacy and biosafety. We have reviewed the recent significant …

Long-wavelength photoconvertible dimeric BODIPYs for super-resolution single-molecule localization imaging in near-infrared emission

Q Gong, X Zhang, W Li, X Guo, Q Wu… - Journal of the …, 2022‏ - ACS Publications
Sulfoxide-bridged dimeric BODIPYs were developed as a new class of long-wavelength
photoconvertible fluorophores. Upon visible-light irradiation, a sulfoxide moiety was …

Click and release: bioorthogonal approaches to “on-demand” activation of prodrugs

X Ji, Z Pan, B Yu, LK De La Cruz, Y Zheng… - Chemical Society …, 2019‏ - pubs.rsc.org
Prodrug approaches represent an excellent solution to certain pharmaceutical issues
commonly encountered in the drug discovery and development process. Along this line, the …

Nanomaterials‐Induced Redox Imbalance: Challenged and Opportunities for Nanomaterials in Cancer Therapy

X Wu, Z Zhou, K Li, S Liu - Advanced Science, 2024‏ - Wiley Online Library
Cancer cells typically display redox imbalance compared with normal cells due to increased
metabolic rate, accumulated mitochondrial dysfunction, elevated cell signaling, and …

Smart nanostructures for cargo delivery: uncaging and activating by light

M Karimi, P Sahandi Zangabad… - Journal of the …, 2017‏ - ACS Publications
Nanotechnology has begun to play a remarkable role in various fields of science and
technology. In biomedical applications, nanoparticles have opened new horizons, especially …