Breast cancer is a heterogeneous disease, divisible into a variable number of clinical
subtypes. A fundamental question is how many etiological classes underlie the clinical …

Importance During the past few decades, the incidence of breast cancer (BC) has been
increasing rapidly in East Asia, and BC is currently the most common cancer in several …

Abstract Background In 2010, Surveillance, Epidemiology, and End Results (SEER)
registries began collecting human epidermal growth factor 2 (HER2) receptor status for …

Cancer is the leading cause of death among Asian Americans, Native Hawaiians, and
Pacific Islanders (AANHPIs). In this report, the American Cancer Society presents AANHPI …

Importance Adjuvant chemotherapy improves outcomes of patients with breast cancer.
However, the optimal timing of chemotherapy initiation is unknown. Delayed administration …

Background Trastuzumab resistance followed by metastasis is a major obstacle for
improving the clinical outcome of patients with advanced human epidermal growth factor …

Currently, resistance to trastuzumab, a human epidermal growth factor receptor 2 (HER2)
inhibitor, has become an important obstacle to improving the clinical outcome of patients …

Introduction Breast cancers are increasingly recognized as heterogeneous based on
expression of receptors for estrogen (ER), progesterone (PR), and human epidermal growth …

Background Breast cancer incidence is higher among black women than white women
before age 40 years, but higher among white women than black women after age 40 years …

Background Resistance to trastuzumab has become a leading cause of mortality in breast
cancer patients and is one of the major obstacles for improving the clinical outcome. Cell …