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[HTML][HTML] Complex interplay between autophagy and oxidative stress in the development of pulmonary disease
W Ornatowski, Q Lu, M Yegambaram, AE Garcia… - Redox biology, 2020 - Elsevier
The autophagic pathway involves the encapsulation of substrates in double-membraned
vesicles, which are subsequently delivered to the lysosome for enzymatic degradation and …
vesicles, which are subsequently delivered to the lysosome for enzymatic degradation and …
Cellular signalling pathways mediating the pathogenesis of chronic inflammatory respiratory diseases: an update
Respiratory disorders, especially non-communicable, chronic inflammatory diseases, are
amongst the leading causes of mortality and morbidity worldwide. Respiratory diseases …
amongst the leading causes of mortality and morbidity worldwide. Respiratory diseases …
Redox signaling at the crossroads of human health and disease
Redox biology is at the core of life sciences, accompanied by the close correlation of redox
processes with biological activities. Redox homeostasis is a prerequisite for human health …
processes with biological activities. Redox homeostasis is a prerequisite for human health …
[HTML][HTML] Mechanisms, pathophysiology and currently proposed treatments of chronic obstructive pulmonary disease
SO Rodrigues, CMC Cunha, GMV Soares, PL Silva… - Pharmaceuticals, 2021 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is one of the leading global causes of
morbidity and mortality. A hallmark of COPD is progressive airflow obstruction primarily …
morbidity and mortality. A hallmark of COPD is progressive airflow obstruction primarily …
[HTML][HTML] Pathobiological mechanisms underlying metabolic syndrome (MetS) in chronic obstructive pulmonary disease (COPD): clinical significance and therapeutic …
Chronic obstructive pulmonary disease (COPD) is a major incurable global health burden
and is currently the 4th largest cause of death in the world. Importantly, much of the disease …
and is currently the 4th largest cause of death in the world. Importantly, much of the disease …
COPD and stroke: are systemic inflammation and oxidative stress the missing links?
Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow
limitation and loss of lung function, and is currently the third largest cause of death in the …
limitation and loss of lung function, and is currently the third largest cause of death in the …
Chronic obstructive pulmonary disease and atherosclerosis: common mechanisms and novel therapeutics
Chronic obstructive pulmonary disease (COPD) and atherosclerosis are chronic irreversible
diseases, that share a number of common causative factors including cigarette smoking …
diseases, that share a number of common causative factors including cigarette smoking …
[HTML][HTML] Phosphodiesterases as therapeutic targets for respiratory diseases
H Zuo, I Cattani-Cavalieri, N Musheshe… - Pharmacology & …, 2019 - Elsevier
Chronic respiratory diseases, such as chronic obstructive pulmonary disease (COPD) and
asthma, affect millions of people all over the world. Cyclic adenosine monophosphate …
asthma, affect millions of people all over the world. Cyclic adenosine monophosphate …
[HTML][HTML] The impact of tobacco cigarettes, va** products and tobacco heating products on oxidative stress
Cells constantly produce oxidizing species because of their metabolic activity, which is
counteracted by the continuous production of antioxidant species to maintain the …
counteracted by the continuous production of antioxidant species to maintain the …
New frontiers in the treatment of comorbid cardiovascular disease in chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease (COPD) is a disease characterised by persistent
airflow limitation that is not fully reversible and is currently the fourth leading cause of death …
airflow limitation that is not fully reversible and is currently the fourth leading cause of death …