[HTML][HTML] Biofilms: Understanding the structure and contribution towards bacterial resistance in antibiotics

P Shree, CK Singh, KK Sodhi, JN Surya… - Medicine in …, 2023 - Elsevier
The biofilm is a bacterial colony wrapped in an auto-produced polymer matrix of
polysaccharides, proteins, and DNA. Bacterial biofilms cause persistent infections because …

Staphylococcus aureus biofilms: recent developments in biofilm dispersal

JL Lister, AR Horswill - Frontiers in cellular and infection microbiology, 2014 - frontiersin.org
Staphylococcus aureus is a major cause of nosocomial and community-acquired infections
and represents a significant burden on the healthcare system. S. aureus attachment to …

Approaches for the inhibition and elimination of microbial biofilms using macromolecular agents

LD Blackman, Y Qu, P Cass, KES Locock - Chemical Society Reviews, 2021 - pubs.rsc.org
Biofilms are complex three-dimensional structures formed at interfaces by the vast majority
of bacteria and fungi. These robust communities have an important detrimental impact on a …

Control of biofilm formation: antibiotics and beyond

A Algburi, N Comito, D Kashtanov… - Applied and …, 2017 - Am Soc Microbiol
Biofilm-associated bacteria are less sensitive to antibiotics than free-living (planktonic) cells.
Furthermore, with variations in the concentration of antibiotics throughout a biofilm, microbial …

Approaches to dispersing medical biofilms

D Fleming, KP Rumbaugh - Microorganisms, 2017 - mdpi.com
Biofilm-associated infections pose a complex problem to the medical community, in that
residence within the protection of a biofilm affords pathogens greatly increased tolerances to …

Innovative strategies toward the disassembly of the EPS matrix in bacterial biofilms

RM Pinto, FA Soares, S Reis, C Nunes… - Frontiers in …, 2020 - frontiersin.org
Bacterial biofilms represent a major concern at a worldwide level due to the high demand for
implantable medical devices and the rising numbers of bacterial resistance. The complex …

Strategy to combat biofilms: a focus on biofilm dispersal enzymes

S Wang, Y Zhao, AP Breslawec, T Liang… - npj Biofilms and …, 2023 - nature.com
Bacterial biofilms, which consist of three-dimensional extracellular polymeric substance
(EPS), not only function as signaling networks, provide nutritional support, and facilitate …

Targeting biofilms therapy: current research strategies and development hurdles

Y Jiang, M Geng, L Bai - Microorganisms, 2020 - mdpi.com
Biofilms are aggregate of microorganisms in which cells are frequently embedded within a
self-produced matrix of extracellular polymeric substance (EPS) and adhere to each other …

Esca** the biofilm in more than one way: desorption, detachment or dispersion

OE Petrova, K Sauer - Current opinion in microbiology, 2016 - Elsevier
Highlights•At least three types of “escapes” or ways for bacteria to leave the biofilm are
known.•Types of escapes are referred to as desorption, detachment, and …

New perspectives in biofilm eradication

H Wolfmeier, D Pletzer, SC Mansour… - ACS infectious …, 2018 - ACS Publications
Microbial biofilms, which are elaborate and highly resistant microbial aggregates formed on
surfaces or medical devices, cause two-thirds of infections and constitute a serious threat to …