Animal Models in Diabetic Research—History, Presence, and Future Perspectives

S Pandey, T Chmelir, M Chottova Dvorakova - Biomedicines, 2023 - mdpi.com
Diabetes mellitus (DM) is a very serious disease, the incidence of which has been
increasing worldwide. The beginning of diabetic research can be traced back to the 17th …

Review on mechanisms of hypoglycemic effects of compounds from highland barley and potential applications

Y Liu, Y Jia, Y Wu, H Zhang, F Ren, S Zhou - Food & Function, 2024 - pubs.rsc.org
The rising prevalence of metabolic diseases, such as diabetes and obesity, presents a
significant global health challenge. Dietary interventions, with their minimal side effects, hold …

Pterostilbene ameliorates type-2 diabetes mellitus–Induced depressive-like behavior by mitigating insulin resistance, inflammation and ameliorating HPA axis …

R Patil, U Aswar, N Vyas - Brain Research, 2023 - Elsevier
One of the most serious mental health comorbidities associated with diabetes mellitus is
depression. The occurrence is almost double in type 2 diabetes mellitus (T2DM) compared …

Novel micronutrient laced biogenic copper oxide nanoparticles for treatment of diabetes in Wistar rats

MN Chalse, UM Aswar, AV Pethkar - Journal of Drug Delivery Science and …, 2023 - Elsevier
Studies were aimed at green synthesis of biogenic copper oxide nanoparticles (CuOnpls)
with antidiabetic activity. The synthesis involved reaction of copper acetate with an aqueous …

Diabetes Mellitus Impairs Blood‐Brain Barrier Integrality and Microglial Reactivity

S Liu, J Hao, T Yu, VV Tuchin, J Li, D Li… - Journal of …, 2025 - Wiley Online Library
Diabetes mellitus (DM), a chronic metabolic disorder that adversely affects the blood–brain
barrier (BBB) and microglial function in the central nervous system (CNS), contributing to …

Antidiabetic, Antioxidant, Antinociceptive, and Anti‐Inflammatory Potential of Chemically Characterized Extract of Limeum Indicum Stocks ex T. Anderson (Aizoaceae) …

R Imran, S Peerzada, I Anjum, HM Bilal… - …, 2024 - Wiley Online Library
Limeum indicum (LI), a plant from the Aizoaceae family, has garnered interest due to its
potential health benefits. In this study, we explore the antidiabetic, antioxidant …

CHEMICAL COMPOSITION AND PHARMACOLOGICAL ACTIVITIES OF FICUS RACEMOSA FRUIT METHANOLIC EXTRACT

H Pant, S Negi, K Saklani, S Chandra… - Pharmacological …, 2025 - Elsevier
ABSTRACT Background Ficus racemosa Linn is a well-known medicinal plant in various
traditional systems of medicine and is used to treat kidney stones, biliary disorders, jaundice …

Epigallocatechin Gallate (EGCG) Mitigates Oxidative Stress and Restores Histological Integrity in Streptozotocin-Induced Zebrafish Model of Diabetes

A Jamir, S Longkumer, PP Pankaj - Current Indian Science, 2024 - benthamdirect.com
Aims The primary aim of this study is to investigate the potential therapeutic effects of
Epigallocatechin gallate (EGCG) in a zebrafish model of diabetes induced by streptozotocin …