Mammalian development demands precision. Millions of molecules must be properly
located in temporal order, and their function regulated, to orchestrate important steps in cell …

The cell cycle is a collection of events by which cellular components such as genetic
materials and cytoplasmic components are accurately divided into two daughter cells. The …

Gametes are highly specialized cell types produced by a complex differentiation process.
Production of viable oocytes requires a series of precise and coordinated molecular events …

The Toll signaling pathway was initially identified for its involvement in the control of early
embryogenesis. It was later shown to be also part of a major innate immune pathway …

Background The formation of matured and individual sperm involves a series of molecular
and spectacular morphological changes of the develo** cysts in Drosophila melanogaster …

Negative regulators of the inflammatory responses are essential for the maintenance of
immune homeostasis and organismal fitness. In Drosophila, the deubiquitinase (Dub) dTrbd …

The alphaproteobacterium Wolbachia pipientis infects arthropod and nematode species
worldwide, making it a key target for host biological control. Wolbachia-driven host …

In eukaryotic cells, RNA-binding proteins (RBPs) interact with RNAs to form
ribonucleoprotein complexes (RNA granules) that have long been thought to regulate RNA …

The asymmetric division of adult stem cells into one self-renewing stem cell and one
differentiating cell is critical for maintaining homeostasis in many tissues. One paradigmatic …

Although of high priority for the development of genetic tools to control malaria-transmitting
mosquitoes, only a few germline-specific regulatory regions have been characterised to date …