Assessing the risk of second malignancies after modern radiotherapy

WD Newhauser, M Durante - Nature Reviews Cancer, 2011 - nature.com
Recent advances in radiotherapy have enabled the use of different types of particles, such
as protons and heavy ions, as well as refinements to the treatment of tumours with standard …

Second solid cancers after radiation therapy: a systematic review of the epidemiologic studies of the radiation dose-response relationship

AB de Gonzalez, E Gilbert, R Curtis, P Inskip… - International Journal of …, 2013 - Elsevier
Rapid innovations in radiation therapy techniques have resulted in an urgent need for risk
projection models for second cancer risks from high-dose radiation exposure, because …

AAPM TG 158: measurement and calculation of doses outside the treated volume from external‐beam radiation therapy

SF Kry, B Bednarz, RM Howell, L Dauer… - Medical …, 2017 - Wiley Online Library
The introduction of advanced techniques and technology in radiotherapy has greatly
improved our ability to deliver highly conformal tumor doses while minimizing the dose to …

Incidence of second malignancies among patients treated with proton versus photon radiation

CS Chung, TI Yock, K Nelson, Y Xu, NL Keating… - International Journal of …, 2013 - Elsevier
Purpose Proton radiation, when compared with photon radiation, allows delivery of
increased radiation dose to the tumor while decreasing dose to adjacent critical structures …

The Linear No-Threshold Relationship Is Inconsistent with Radiation Biologic and Experimental Data1

M Tubiana, LE Feinendegen, C Yang, JM Kaminski - Radiology, 2009 - pubs.rsna.org
The carcinogenic risk induced by low doses of ionizing radiation is controversial. It cannot
be assessed with epidemiologic methods alone because at low doses the data are …

Proton vs carbon ion beams in the definitive radiation treatment of cancer patients

H Suit, T DeLaney, S Goldberg, H Paganetti… - Radiotherapy and …, 2010 - Elsevier
BACKGROUND AND PURPOSE: Relative to X-ray beams, proton [1H] and carbon ion [12C]
beams provide superior distributions due primarily to their finite range. The principal …

Molecular mechanisms of resveratrol as chemo and radiosensitizer in cancer

S Cotino-Nájera, LA Herrera… - Frontiers in …, 2023 - frontiersin.org
One of the primary diseases that cause death worldwide is cancer. Cancer cells can be
intrinsically resistant or acquire resistance to therapies and drugs used for cancer treatment …

Can we reduce the incidence of second primary malignancies occurring after radiotherapy? A critical review

M Tubiana - Radiotherapy and Oncology, 2009 - Elsevier
Second primary malignancies (SPMs) occurring after oncological treatment have become a
major concern during the past decade. Their incidence has long been underestimated …

Review and evaluation of updated research on the health effects associated with low-dose ionising radiation

LT Dauer, AL Brooks, DG Hoel… - Radiation Protection …, 2010 - academic.oup.com
While radiation health risks at low doses have traditionally been estimated from high-dose
studies, we have reviewed recent literature and concluded that the mechanisms of action for …

Dosimetry of ionising radiation in modern radiation oncology

T Kron, J Lehmann, PB Greer - Physics in Medicine & Biology, 2016 - iopscience.iop.org
Dosimetry of ionising radiation is a well-established and mature branch of physical sciences
with many applications in medicine and biology. In particular radiotherapy relies on …