Methods to specifically profile protease activity at lymph nodes

SN Bhatia, DJ Irvine, KD Wittrup, AD Warren… - US Patent …, 2022 - Google Patents
In some aspects, the disclosure provides compositions and methods for detecting and
monitoring the activity of pro teases in vivo using affinity assays. The disclosure relates, in …

Lung protease nanosensors and uses thereof

SN Bhatia, J Kirkpatrick, JS Dudani, C Buss… - US Patent App. 16 …, 2020 - Google Patents
2020-02-27 Assigned to MASSACHUSETTS INSTITUTE OF TECHNOLOGY reassignment
MASSACHUSETTS INSTITUTE OF TECHNOLOGY ASSIGNMENT OF ASSIGNORS …

Inhalable nanosensors with volatile reporters and uses thereof

SN Bhatia, LWG Chan, RR Kunz - US Patent 11,054,428, 2021 - Google Patents
In some aspects, the disclosure relates to compositions and method for detection,
classification, and treatment of disease or other body status. The methods and compositions …

Methods to spatially profile protease activity in tissue and sections

SN Bhatia, JS Dudani, EJ Kwon… - US Patent 11,519,905, 2022 - Google Patents
Aspects of the disclosure relate to methods and composi tions useful for in vivo and/or in
vitro enzyme profiling. In some embodiments, the disclosure provides methods of in vivo …

Methods and products for in vivo enzyme profiling

SN Bhatia, GA Von Maltzahn, GA Kwong - US Patent 10,883,998, 2021 - Google Patents
The present invention relates to methods and products associated with in vivo enzyme
profiling. In particular, the invention relates to methods of in vivo processing of exog enous …

Methods and products for in vivo enzyme profiling

SN Bhatia, GA Von Maltzahn, GA Kwong - US Patent 11,703,510, 2023 - Google Patents
The present invention relates to methods and products associated with in vivo enzyme
profiling. In particular, the invention relates to methods of in vivo processing of exogenous …

Methods and products for in vivo enzyme profiling

SN Bhatia, GA Von Maltzahn, GA Kwong - US Patent 11,549,951, 2023 - Google Patents
US11549951B2 - Methods and products for in vivo enzyme profiling - Google Patents
US11549951B2 - Methods and products for in vivo enzyme profiling - Google Patents …

[PDF][PDF] Método de preparo e caracterização de nanocarreadores proteicos para liberação de compostos botânicos por estímulos ambientais e respectivas formulações

LF Fraceto, JL Oliveira, LB Carvalho, MC Camara… - 2022 - repositorio.unesp.br
[001] A presente patente de invenção trata de método de preparo e caracterização de
nanocarreadores proteícos para liberação de compostos botânicos por estímulos …

Sensors for detecting and imaging of cancer metastasis

SN Bhatia, L Hao - US Patent 11,835,522, 2023 - Google Patents
2020-02-26 Assigned to MASSACHUSETTS INSTITUTE OF TECHNOLOGY reassignment
MASSACHUSETTS INSTITUTE OF TECHNOLOGY ASSIGNMENT OF ASSIGNORS …

Bodily processing of activity sensors

S Bhatia, G Kwong, E Huang, SR Banerjee… - US Patent App. 16 …, 2020 - Google Patents
The invention provides methods and compositions that use a process in the body to deliver
an active form of the activity sensor to a target site within the body. The activity sensors …