A state-of-the-art methodology for high-throughput in silico vaccine discovery against protozoan parasites and exemplified with discovered candidates for Toxoplasma …

SJ Goodswen, PJ Kennedy, JT Ellis - Scientific Reports, 2023 - nature.com
Vaccine discovery against eukaryotic parasites is not trivial as highlighted by the limited
number of known vaccines compared to the number of protozoal diseases that need one …

RPA-CRISPR/Cas12a-LFA combined with a digital visualization instrument to detect Toxoplasma gondii in stray dogs and cats in Zhejiang province, China

H Sun, J Fan, H Chu, Y Gao, J Fang, Q Wu… - Microbiology …, 2024 - journals.asm.org
Toxoplasma gondii, which causes toxoplasmosis, is prevalent in warm-blooded animals,
such as cats, dogs, and humans. T. gondii causes economic losses to livestock production …

Stable and ancient endocytic structures navigate the complex pellicle of apicomplexan parasites

L Koreny, BN Mercado-Saavedra, CM Klinger… - bioRxiv, 2022 - biorxiv.org
Apicomplexan parasites have an immense impact on humanity, but their basic cellular
processes are often poorly understood. The sites of endocytosis, the conservation of this …

[PDF][PDF] A large-scale study on the seroprevalence of Toxoplasma gondii infection in humans in Iran.

R Kalantari, M Esmaeilifallah, R Jafari… - Folia …, 2023 - researchgate.net
It is estimated that nearly one-third of the world's human population is infected with
Toxoplasma gondii (Nicolle et Manceaux, 1908). Human infection is commonly …

Mitochondrial ADP/ATP Carrier 1 Is Important for the Growth of Toxoplasma Tachyzoites

J Qian, T Zhao, L Guo, S Li, Z He, M He… - Microbiology …, 2023 - journals.asm.org
Metabolism associated with energy production is highly compartmentalized in eukaryotic
cells. During this process, transporters that move metabolites across organelle membranes …

Single and combination treatment of Toxoplasma gondii infections with a bumped kinase inhibitor and artemisone in vitro and with artemiside in experimentally …

C Schlange, J Müller, D Imhof, KPA Hänggeli… - Experimental …, 2023 - Elsevier
In previous studies, the artemisinin derivatives artemisone, its pro-drug artemiside and the
bumped-kinase inhibitor BKI-1748 were effective against T. gondii via different modes of …

[PERNYATAAN][C] Frecuencia serológica y factores de riesgo asociados a Toxoplasma Gondii en gatos, de consultorios de la ciudad de Lima

CIG CUBA - 2023 - Universidad Nacional Mayor de San …