The extended use of androgen deprivation therapy (ADT) may often lead to the progression
from castration‐sensitive prostate cancer (CSPC) to castration‐resistant prostate cancer …

Centriole integrity, vital for cilia formation and chromosome segregation, is crucial for human
health. The inner scaffold within the centriole lumen composed of the proteins POC1B …

Centrioles are unique cellular structures that replicate to produce identical copies, ensuring
accurate chromosome segregation during mitosis. A new centriole, the “daughter”, is …

Apicomplexans, a large phylum of protozoan intracellular parasites, well known for their
ability to invade and proliferate within host cells, cause diseases with major health and …

Microbial eukaryotes are small and often resistant to standard labelling and imaging
techniques, and therefore remain understudied–despite their critical ecological importance …

Centrosomes have critical roles in microtubule organization, ciliogenesis, and cell signaling.
1, 2, 3, 4, 5, 6, 7, 8 Centrosomal alterations also contribute to diseases, including …

Tightly coordinated cell cycle regulation is essential for homeostasis. G0, or quiescence, is
especially crucial for cells to respond to extracellular stimuli. Little is known about the …

The interplay of the three-dimensional (3D) distribution of various subcellular components
and their interactions are expected to control overall cellular morphology in biology. In this …

Centrioles have a unique, conserved architecture formed by three linked “triplet”
microtubules arranged in nine-fold symmetry. The mechanisms by which these triplet …

Centrioles play central roles in ciliogenesis and mitotic spindle assembly. Once assembled,
centrioles exhibit long-term stability, a property essential for maintaining numerical control …